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2015v1.0
,Kaplan’s Essentials of
Cardiac Anesthesia for
Cardiac Surgery
,This page intentionally left blank
,Kaplan’s Essentials of
Cardiac Anesthesia
for Cardiac Surgery
Second Edition
Editor
Joel A. Kaplan, MD, CPE, FACC
Professor of Anesthesiology
University of California, San Diego
La Jolla, California
Dean Emeritus
School of Medicine
Former Chancellor
Health Sciences Center
University of Louisville
Louisville, Kentucky
Associate Editors
Brett Cronin, MD
Assistant Clinical Professor
Department of Anesthesiology
University of California, San Diego
La Jolla, California
Timothy Maus, MD, FASE
Associate Clinical Professor
Director of Perioperative Echocardiography
Department of Anesthesiology
University of California, San Diego
La Jolla, California
,1600 John F. Kennedy Blvd.
Ste 1800
Philadelphia, PA 19103-2899
KAPLAN’S ESSENTIALS OF CARDIAC ANESTHESIA FOR ISBN: 978-0-323-49798-5
CARDIAC SURGERY, SECOND EDITION
Copyright © 2018 by Elsevier, Inc. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic
or mechanical, including photocopying, recording, or any information storage and retrieval system,
without permission in writing from the Publisher. Details on how to seek permission, further
information about the Publisher’s permissions policies, and our arrangements with organizations such
as the Copyright Clearance Center and the Copyright Licensing Agency can be found at our website:
www.elsevier.com/permissions.
This book and the individual contributions contained in it are protected under copyright by the
Publisher (other than as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new research and experience
broaden our understanding, changes in research methods, professional practices, or medical
treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in
evaluating and using any information, methods, compounds, or experiments described herein. In
using such information or methods, they should be mindful of their own safety and the safety of
others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check
the most current information provided (i) on procedures featured or (ii) by the manufacturer of
each product to be administered, to verify the recommended dose or formula, the method and
duration of administration, and contraindications. It is the responsibility of practitioners, relying
on their own experience and knowledge of their patients, to make diagnoses, to determine dosages
and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors
assume any liability for any injury and/or damage to persons or property as a matter of products
liability, negligence, or otherwise or from any use or operation of any methods, products,
instructions, or ideas contained in the material herein.
Previous edition copyrighted 2008
Library of Congress Cataloging-in-Publication Data
Names: Kaplan, Joel A., editor. | Cronin, Brett, editor. | Maus, Timothy, editor.
Title: Kaplan’s essentials of cardiac anesthesia for cardiac surgery / editor,
Joel A. Kaplan ; associate editors, Brett Cronin, Timothy Maus.
Other titles: Essentials of cardiac anesthesia. | Essentials of cardiac anesthesia
for cardiac surgery
Description: Second edition. | Philadelphia, PA : Elsevier, [2018] | Preceded
by Essentials of cardiac anesthesia / [edited by] Joel A. Kaplan. c2008. |
Includes bibliographical references and index.
Identifiers: LCCN 2017042688 | ISBN 9780323497985 (pbk. : alk. paper)
Subjects: | MESH: Anesthesia | Cardiac Surgical Procedures | Heart–drug
effects | Heart Diseases–surgery
Classification: LCC RD87.3.C37 | NLM WG 460 | DDC 617.9/6741–dc23
LC record available at https://lccn.loc.gov/2017042688
Executive Content Strategist: Dolores Meloni
Senior Content Development Specialist: Ann Anderson
Publishing Services Manager: Catherine Albright Jackson
Senior Project Manager: Doug Turner
Designer: Ryan Cook
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
,Dedication
To all of the residents and fellows in cardiac anesthesia with whom we have been
fortunate to work over the past decades and to Norma, my loving wife of more than
50 years.
JAK
To my two girls, Hayley and Berkeley.
BC
To my wife, Molly, and my children, William, Owen, and Winston, for all of your love
and support.
TM
v
,This page intentionally left blank
,Contributors
Shamsuddin Akhtar, MBBS Daniel Bainbridge, MD
Associate Professor Associate Professor
Department of Anesthesiology and Department of Anesthesia and
Pharmacology Perioperative Medicine
Yale University School of Medicine Western University
New Haven, Connecticut London, Ontario, Canada
Sarah Armour, MD Dalia A. Banks, MD, FASE
Instructor Clinical Professor of Anesthesiology
Anesthesiology Director, Cardiac Anesthesia
Mayo Clinic University of California, San Diego
Rochester, Minnesota La Jolla, California
William R. Auger, MD Manish Bansal, MD, DNB
Professor of Clinical Medicine CARDIOLOGY, FACC, FASE
Division of Pulmonary and Critical Senior Consultant
Care Medicine Department of Cardiology
University of California, San Diego Medanta—The Medicity
La Jolla, California Gurgaon, Haryana, India
John G.T. Augoustides, MD, Paul G. Barash, MD
FASE, FAHA Professor
Professor of Anesthesiology and Department of Anesthesiology
Critical Care Yale University School of Medicine
Perelman School of Medicine New Haven, Connecticut
Hospital of the University of
Pennsylvania Victor C. Baum, MD
Philadelphia, Pennsylvania US Food and Drug Administration
Silver Spring, Maryland
Gina C. Badescu, MD Departments of Anesthesiology and
Attending Anesthesiologist Critical Care Medicine and Pediatrics
Bridgeport Hospital George Washington University
Stratford, Connecticut Washington, District of Columbia
James M. Bailey, MD Elliott Bennett-Guerrero, MD
Medical Director Professor and Vice Chair
Critical Care Clinical Research and Innovation
Northeast Georgia Health System Department of Anesthesiology
Gainesville, Georgia Stony Brook University School of
Medicine
Stony Brook, New York
vii
, Dan E. Berkowitz, MD Davy C.H. Cheng, MD, MSC
CONTRIBUTORS
Professor Distinguished University Professor
Anesthesiology and Critical Care and Chair
Medicine Department of Anesthesia and
Division of Cardiothoracic Anesthesia Perioperative Medicine
Johns Hopkins University School of Western University
Medicine London, Ontario, Canada
Baltimore, Maryland
Albert T. Cheung, MD
Martin Birch, MD Professor
Anesthesiologist and Critical Care Department of Anesthesiology
Physician Stanford University School of
Hennepin County Medical Center Medicine
Minneapolis, Minnesota Stanford, California
Simon C. Body, MD Joanna Chikwe, MD
Associate Professor of Anesthesia Professor of Surgery
Harvard Medical School Co-Director, Heart Institute
Brigham and Women’s Hospital Chief, Cardiothoracic Surgery Division
Boston, Massachusetts Stony Brook University School of
Medicine
T. Andrew Bowdle, MD, Stony Brook, New York
PhD, FASE
David J. Cook, MD
Professor of Anesthesiology and
Pharmaceutics Emeritus Professor of Anesthesiology
University of Washington Mayo Clinic
Seattle, Washington Rochester, Minnesota
Chief Clinical and Operating Officer
Charles E. Chambers, MD Jiahui Health
Professor of Medicine and Radiology Shanghai, China
Heart and Vascular Institute
Ryan C. Craner, MD
Penn State Hershey Medical Center
Hershey, Pennsylvania Senior Associate Consultant
Anesthesiology
Mark A. Chaney, MD Mayo Clinic
Professor and Director of Cardiac Phoenix, Arizona
Anesthesia
Duncan G. de Souza,
Anesthesia and Critical Care
The University of Chicago MD, FRCPC
Chicago, Illinois Clinical Assistant Professor
Department of Anesthesiology
Alan Cheng, MD University of British Columbia
Adjunct Associate Professor Vancouver, British Columbia, Canada
Johns Hopkins University School of Director
Medicine Cardiac Anesthesia
Baltimore, Maryland Kelowna General Hospital
Kelowna, British Columbia, Canada
viii