PATHOPHYSIOLOGY NR 283 EXAM 2 LECTURE NOTES
ACCURATE & VERIFIED GUARANTEED PASS
Fluid and Electrolytes Week 3:
2 major 昀氀uid compartments-
• Extracellular (intravascular/interstitial) (outside the cell)
o I’m stuck between the cells- interstitial (昀氀oading inbetween)
o I’m swimming in the capillaries – intravascular (昀氀uid that make
up our extracellular 昀氀uid)
• Intracellular (inside the cell)
,Maintaining Fluid Balance
• Body is 60% water
• Thirst mechanism
o Located in hypothalamus -> osmoreceptors identify 昀氀uid
o Volume & concentration -> promotes the intake of 昀氀uid
• ADH (know)
o Controls amount of 昀氀uid leaving the body via urine
o Promotes reabsorption of water into the blood from the kidney
tubules
o Aldosterone
o Will get reabsorbed back into your body from the kidneys so you
can hold onto it
o If you are dehydrated this is what will help
,• ANP/BNP
o Released by the cardiac muscle 昀椀bers in response to increased
pressure within the cardiac chambers
o Excretes water & sodium, retains potassium
o If to much water in your body this will help pee it out
• Aldossssterone
o Reabsorption of water & ssssodium from the kidney tubules,
excretes potassium
o It is going to hold on to the sodium
o If you are dehydrated this is what will help
, Hyperosmolar- concentrated hypoosmolar- to much water so
release ANP/BNP
What Moves Me? (pressures important)!!
• Fluid and solute from blood vessel (intravascular) to interstitial
compartment (arteriole)
• Fluid from interstitial compartment to blood vessel (intravascular)
• Hydrostatic pressure- Stay away, pushing pressure
ACCURATE & VERIFIED GUARANTEED PASS
Fluid and Electrolytes Week 3:
2 major 昀氀uid compartments-
• Extracellular (intravascular/interstitial) (outside the cell)
o I’m stuck between the cells- interstitial (昀氀oading inbetween)
o I’m swimming in the capillaries – intravascular (昀氀uid that make
up our extracellular 昀氀uid)
• Intracellular (inside the cell)
,Maintaining Fluid Balance
• Body is 60% water
• Thirst mechanism
o Located in hypothalamus -> osmoreceptors identify 昀氀uid
o Volume & concentration -> promotes the intake of 昀氀uid
• ADH (know)
o Controls amount of 昀氀uid leaving the body via urine
o Promotes reabsorption of water into the blood from the kidney
tubules
o Aldosterone
o Will get reabsorbed back into your body from the kidneys so you
can hold onto it
o If you are dehydrated this is what will help
,• ANP/BNP
o Released by the cardiac muscle 昀椀bers in response to increased
pressure within the cardiac chambers
o Excretes water & sodium, retains potassium
o If to much water in your body this will help pee it out
• Aldossssterone
o Reabsorption of water & ssssodium from the kidney tubules,
excretes potassium
o It is going to hold on to the sodium
o If you are dehydrated this is what will help
, Hyperosmolar- concentrated hypoosmolar- to much water so
release ANP/BNP
What Moves Me? (pressures important)!!
• Fluid and solute from blood vessel (intravascular) to interstitial
compartment (arteriole)
• Fluid from interstitial compartment to blood vessel (intravascular)
• Hydrostatic pressure- Stay away, pushing pressure
