What is osteomyelitis? - ANSWER Severe infection of the bone, bone
marrow, and surrounding soft tissue
The most common causative agent of osteomyelitis - ANSWER
Staphylococcus aureus
Two ways an osteomyelitis infection can occur - ANSWER direct (open
wound directly to the site of bone, implants)
indirect (pathogen carried to the bone by vascular network)
What is a sequestrum? - ANSWER piece of dead bone
usually within a bone (not directly at the edge of the bone - may be
surrounded by healthy bone, which makes it very difficult to access and
tx with therapies)
Risk of a sequestrum - ANSWER may serve as a reservoir for micro
organisms can spread to other sites
Acute osteomyelitis has what period of duration - ANSWER less than
one month
local sx/sx of acute osteomyelitis - ANSWER pain that is unrelieved by
rest and worsens with activity
swelling
tenderness
, warmth at the infection site
restricted movement of the affected part.
systemic sx/sx of acute osteomyelitis - ANSWER fever
night sweats
chills
restlessness
nausea
malaise.
Chronic osteomyelitis has a duration of - ANSWER 1 month or more
***or failed response to first tx with antibiotics
Granulation tissue growth in the cases of chronic osteomyelitis are
cause for concern because.. - ANSWER scar tissue responds in reaction
and medications are no longer able to penetrate site of infection
Diagnostic studies for osteomyelitis include - ANSWER -bone or soft
tissue biopsy (definitive way to identify micro organism)
Elevated WBC and ESR
x-rays, bone scan, MRI, CT
Radionuclide bone scan (gallium and indium)
Surgical debridement and decompression often needed for acute or
chronic osteomyelitis - ANSWER chronic
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