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SBB Genetic, Rh and RBC membrane Exam |Questions with 100% Correct Answers
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SBB Genetic, Rh and RBC membrane Exam |Questions with 100% Correct Answers
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SBB Genetic, Rh and RBC membraneExam |Questions with 100% Correct
Answers
RHD - ✔The absence or mutation of the _____________gene makes a person D negative
True - ✔The C/c and E/e antigens are found on a single protein
True or False
True - ✔Some partial D's can type as Rh negative
True or False
Rosenfeld - ✔Of the three RH nomenclatures Fisher Race, Weiner, Rosenfield which is
devoid of inheritance theory?
The 1980s - ✔What decade was the start of Rh molecular biology and purification of Rh
D polypeptides
The 1990s - ✔What decade started the cloning of Rh genes and molecular bases of D+ and D -
phenotypes
RHD gene - ✔Polypeptide carries the D antigen on the _____________ gene
True - ✔Rh proteins are neither glycosylated nor phosphorylated which means there are
no carbohydrates attached to proteins
, True or False
Inerchain - ✔Chemically modified anti-D is used in determining Rh positive rosettes it
splits the _________________disulfide bonds
Definition of blood groups - ✔Blood groups are defined by individual differences in
proteins and/or carbohydrates that make up part of the red blood cell membrane
Blood group systems, collections, series - ✔Blood groups may be divided into three categories
Undefined - ✔The _____________ antigens have been placed in a collection or series by the
ISBT working party until final designation has been completed
The antigens within the various collections have serological, biochemical and genetic
relationship but do not for fill a criteria for systems status is - ✔Collections
The blood group antigens appear to be unique unto themselves. There are two groups.
700 series Lows 901 series highs - ✔Describe the series in blood group antigens
700 series Low's = < 1% of most population studied and or not known to belong to a
blood group system
901 series occurs in
> 90% of populations and are not known to belong to a blood group system - ✔Explain the
700 and 901 series
5' to 3' - ✔Transcripts are single stranded RNA copies of DNA that run in which
prime directions?
Define synonymous, missense, nonsense SNP - ✔Synonymous SNP is silent and does not
result in an amino acid change
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