NR606 Week 4 Exam with Questions and Answers

NR606 Week 4 Exam with Questions and Answers develop schizophrenia ANSWER -Many genes play a role • as do epigenetic factors • Heritability as high as 79% -gene-environment interaction -Environmental Triggers: • Regular Cannabis Use • Exposure to Early Life Trauma Sexual Abuse Emotional Abuse Emotional Neglect Bullying schizophrenia Neuroanatomy ANSWER -Mesocortical & ventromedial prefrontal cortex: negative and affective symptoms -Dorsolateral: cognitive symptoms -Orbitofrontal & connections to the amygdala: aggressive, impulsive symptoms Brain Circuits Affected in Schizophrenia: ANSWER -Dopamine Pathways • explain the (+) & (-) symptoms seen in schizophrenia & psychosis Dopamine Role in Psychosis ANSWER -leading hypothesis • psychosis & schizophrenia associated with dysfunction of neurotransmitter dopamine (DA)