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MBG 2040 with 100- correct answers 2025.
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MBG 2040 with 100- correct answers 2025.
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MBG 2040 with 100%correct answers 2025
Null.Amorphic alleles - answer 2 options
- either a nonfunctional protein is produced
- no protein is produced
"useless or none"
Hypomoprhic Alleles: - answer 2 options
- either poorly/partial functioning protein is produced OR
- reduced amounts of a normally functioning protein is produced
"poorly, less amount"
Dominant Hypermorphic Alleles - answer (1) Negative phenotypic
consequences
- due to the over-production of a normal protein OR
- due to the production of a protein with increased activity levels.
"too much"
neomorphic allele - answer negative phenotypic consequences due too...
- presence of an altered protein with a new function
,- altered protein interferes with wildtype protein (dominant- negative
allele)
complete dominance - answer a relationship in which one allele is
completely dominant over another
incomplete dominance - answer Situation in which one allele is not
completely dominant over another allele:
end up with an intermediate which is a blend of both alleles
ex. flower colour (red,white,pink) example
Codominance - answer A condition in which neither of two alleles of a
gene is dominant or recessive.
end up with a situation where both alleles are present
ex. blood type
true or false: multiple alleles often exist for a gene at a particular locus -
answer TRUE: think of the example on the slide about multiple allelic
forms (mutants) of the wild type gene (A)
Allelic/Dominance Series - answer describes the dominance hierarchy of
multiple alleles
IA and IB are what type of dominance? - answer they are codominant
A transferase - answer encoded by IA & IB
responsible for adding acetylgalactosamine and galactose respectively
, i encodes ______________ transferase - answer nonfunctional
Why is blood type O the universal donor? - answer There are no antigens
that can be recognized as foreign as it encodes a non-functional
transferase which therefore does not add any anitgens onto the cell
** not 100% sure about this "fact" of why there r no antigens
name the "antigen" type AB blood have - answer BOTH galactose and
aceytlgalactosamine
wildtype allele - answer a functional enzyme or other protein is produced
term wildtype is also used to refer to the most common
phenotype/genotype found in a natural population
loss of function allele - answer an enzyme or other protein is no longer
being produced, is produced at lower levels, or is nonfunctional
true or false: the loss of function allele is dominant over the wildtype
allele - answer false, the other way around
Haplosufficiency - answer Half as much protein is synthesized yet this is
often sufficient to achieve the wildtype phenotype
true or false the dominant allele is always normal and the recessive allele
is always a mutation? - answer false, not always
provide an example where the dominant allele is not normal - answer
Huntington's disease - in this case dominant allele is a "gain of function"
mutation and the mutant allele produces a protein with
increased(detrimental) function
**dominant alleles can be gain of function mutations**
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