ECPI PHARMACOLOGY EXAM #1
QUESTIONS AND ANSWERS
NicotinicN - Answer-receptor subtype located in all autonomic nervous system ganglia
and in the adrenal medulla
NicotinicN - Answer-receptor that stimulates parasympathetic and sympathetic
postganglionic nerves and releases epinephrine form the adrenal medulla
NicotinicM - Answer-receptor subtype located in the neuromuscular junction
NicotinicM - Answer-receptor that causes contraction of skeletal muscle
Muscarinic - Answer-receptor subtype that targets parasympathetic organs
Muscarinic - Answer-receptor subtype that is located in the eye, heart, lungs, bladder,
GI Tract, sweat glands, sex organs, and blood vessels
Muscarinic - Answer-when activated, this receptor subtype causes coordinated
contraction of detrusor and relaxation of the trigone and sphincter which causes voiding
of the bladder
Muscarinic - Answer-receptor subtype that causes vasodilation of the blood vessels
Muscarinic - Answer-receptor that causes constriction of bronchi
cholinergic - Answer-NicotinicN, NicotinicM, and Muscarinic are all _______ receptor
subtypes
miosis - Answer-decreased pupil diameter
mydriasis - Answer-increased pupil size
Alpha1 - Answer-receptor subtype that causes mydriasis, arteriole constriction in the
skin, viscera, and mucous membranes, ejaculation, contraction of the prostatic capsule,
and contraction of the trigone and bladder sphincter
Alpha2 - Answer-receptor subtype leads to Inhibition of transmitter release in
presynaptic nerve terminals
Beta1 - Answer-receptor subtype that leads to increased HR, force of contraction,
speed of AV conduction, and causes the release of renin in the kidneys
, Beta2 - Answer-receptor subtype that causes dilation of arterioles in the heart, lungs,
and skeletal muscles, bronchial dilation, uterine relaxation, glycogenolysis, and
enhanced contraction of skeletal muscles
Dopamine - Answer-receptor subtype that effects the kidney by dilating its vasculature
adrenergic - Answer-alpha1, alpha2, beta1, beta2, and dopamine are all _____ receptor
subtypes
Bethanechol - Answer-medication used to treat non-obstructive urinary retention
Bethanechol - Answer-medication that's investigational use is to treat gastroesophageal
reflux
Bethanechol - Answer-medication shouldn't be used with someone who has latent or
active asthma, because it causes bronchial constriction
Bethanechol - Answer-med that should be taken without food (to avoid
nausea/vomiting), so administered 1 hour before meals or 2 hours after meals
Glaucoma - Answer-Pilocarpine acts by lowering intraocular pressure in the eyes which
treats ________
Myasthenia gravis - Answer-a condition that causes DIFFICULTY SWALLOWING,
ptosis, fatigue, and muscle weakmess
Therapeutic uses for neuromuscular blockers - Answer--muscle relaxation during
surgery
-facilitation of mechanical ventilation
-adjunct to electroconvulsive therapy
-endotracheal intubation
-diagnosis of myasthenia gravis
Myasthenia Gravis
Electrolyte disturbances - Answer-Precautions/Contraindications for competitive
neuromuscular blockers
Enhance, reduce - Answer-In pts with electrolyte disturbances, competitve
neuromuscular blockers would be problematic because low levels of K+ can ______
paralysis, while high levels of K+ can ______ paralysis
Increased urine output and cardiac improvement - Answer-How do you check if
dopamine is effectively treating shock?
cardiac output, renal perfusion - Answer-Dopamine, when given for shock, increases
______ _______ and _______ ________
QUESTIONS AND ANSWERS
NicotinicN - Answer-receptor subtype located in all autonomic nervous system ganglia
and in the adrenal medulla
NicotinicN - Answer-receptor that stimulates parasympathetic and sympathetic
postganglionic nerves and releases epinephrine form the adrenal medulla
NicotinicM - Answer-receptor subtype located in the neuromuscular junction
NicotinicM - Answer-receptor that causes contraction of skeletal muscle
Muscarinic - Answer-receptor subtype that targets parasympathetic organs
Muscarinic - Answer-receptor subtype that is located in the eye, heart, lungs, bladder,
GI Tract, sweat glands, sex organs, and blood vessels
Muscarinic - Answer-when activated, this receptor subtype causes coordinated
contraction of detrusor and relaxation of the trigone and sphincter which causes voiding
of the bladder
Muscarinic - Answer-receptor subtype that causes vasodilation of the blood vessels
Muscarinic - Answer-receptor that causes constriction of bronchi
cholinergic - Answer-NicotinicN, NicotinicM, and Muscarinic are all _______ receptor
subtypes
miosis - Answer-decreased pupil diameter
mydriasis - Answer-increased pupil size
Alpha1 - Answer-receptor subtype that causes mydriasis, arteriole constriction in the
skin, viscera, and mucous membranes, ejaculation, contraction of the prostatic capsule,
and contraction of the trigone and bladder sphincter
Alpha2 - Answer-receptor subtype leads to Inhibition of transmitter release in
presynaptic nerve terminals
Beta1 - Answer-receptor subtype that leads to increased HR, force of contraction,
speed of AV conduction, and causes the release of renin in the kidneys
, Beta2 - Answer-receptor subtype that causes dilation of arterioles in the heart, lungs,
and skeletal muscles, bronchial dilation, uterine relaxation, glycogenolysis, and
enhanced contraction of skeletal muscles
Dopamine - Answer-receptor subtype that effects the kidney by dilating its vasculature
adrenergic - Answer-alpha1, alpha2, beta1, beta2, and dopamine are all _____ receptor
subtypes
Bethanechol - Answer-medication used to treat non-obstructive urinary retention
Bethanechol - Answer-medication that's investigational use is to treat gastroesophageal
reflux
Bethanechol - Answer-medication shouldn't be used with someone who has latent or
active asthma, because it causes bronchial constriction
Bethanechol - Answer-med that should be taken without food (to avoid
nausea/vomiting), so administered 1 hour before meals or 2 hours after meals
Glaucoma - Answer-Pilocarpine acts by lowering intraocular pressure in the eyes which
treats ________
Myasthenia gravis - Answer-a condition that causes DIFFICULTY SWALLOWING,
ptosis, fatigue, and muscle weakmess
Therapeutic uses for neuromuscular blockers - Answer--muscle relaxation during
surgery
-facilitation of mechanical ventilation
-adjunct to electroconvulsive therapy
-endotracheal intubation
-diagnosis of myasthenia gravis
Myasthenia Gravis
Electrolyte disturbances - Answer-Precautions/Contraindications for competitive
neuromuscular blockers
Enhance, reduce - Answer-In pts with electrolyte disturbances, competitve
neuromuscular blockers would be problematic because low levels of K+ can ______
paralysis, while high levels of K+ can ______ paralysis
Increased urine output and cardiac improvement - Answer-How do you check if
dopamine is effectively treating shock?
cardiac output, renal perfusion - Answer-Dopamine, when given for shock, increases
______ _______ and _______ ________