BPS 2110 - Final Exam Questions and Answers 100% Solved
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Course
BPS
Institution
BPS
BPS 2110 - Final Exam Questions and
Answers 100% Solved
What is the goal of Phase 1 of Clinical Trials? - Dose Finding
How many patients are involved in Phase 1 of Clinical Trials? - Small
number (<100)
What type of patients are involved in Phase 1 of Clinical Trials? -
Healthy volunteers
...
What are two key difficulties associated with natural products in terms of
drug development? - ✔✔-Chemical synthesis of related compounds is
difficult.
-Limited to chemical modifications of the natural product.
Describe how drug companies perform safety testing during drug
development. - ✔✔-In-vitro testing, using biochemical assays, and looking
for a "clean" profile.
-Animal testing
List 4 different types of excipients and briefly explain their importance for
formulation. - ✔✔-Preservatives: Prevent mold and bacterial growth.
-Disintegrants: "Blows" the pill apart in the stomach.
-Binders: Hold ingredients together.
-Stabilizers: Protect from chemical degradation due to oxygen.
List 4 different types of formulation and provide a key advantage and
disadvantage of each. - ✔✔-Pills: Most convenient, does not by-pass the
liver.
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