EEOB 2520 Exam 11 Study Guide
Solutions
importance of cortisol - ANSWER-no cortisol = dead within days
Adrenal Insufficiency (Addison's Disease) - ANSWER-below normal levels of cortisol. People with
adrenal insufficency will be weak because cortisol puts energy in the system, have low glucose l...
-increase glucose catabolism (breakdown sugar to supply E for protein synthesis)
-increase adipose catabolism (breakdown fat tissue for energy to grow new cells)
-increase bone growth at epiphyseal plate (non adult growth, steroids fuse bone plate= no more growth)
why is it a bigger issue when kids break bones? - ANSWER✔✔-growth plate could be damaged and
cannot be repaired
control of growth - ANSWER✔✔--growth hormone (GH= E2) is highest during development and at night
-GH will stimulate IGF-1 (E3) (impacts liver and bones) to increase mitosis, stimulate muscle
development (b/c GH binds to receptors in muscle cells), mobilizes nutrients to convert to proteins to
grow new cells, increases fatty acids and glucose in blood
T3/T4 impact on growth - ANSWER✔✔-allows for growth hormone impact on bones
insulin's impact on growth - ANSWER✔✔-increases protein synthesis and is a possible IGF-1 agonist
sex endocrine's impact on growth - ANSWER✔✔-impact growth out not up
cortisol impact on growth - ANSWER✔✔-inhibits GH secretion and effects
calcium regulation - ANSWER✔✔-99% is crystalline in bones (not static)
0.9% is intracellular: in soft tissues (ex: SR in muscle)
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