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APEA MyQ Bank - Principles of Pharmacology QUESTIONS AND ANSWERS WITH VERIFIED SOLUTIONS 100% CORRECT
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APEA MyQ Bank - Principles of Pharmacology QUESTIONS AND ANSWERS WITH VERIFIED SOLUTIONS 100% CORRECT

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  • October 30, 2024
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  • 2024/2025
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APEA MyQ Bank - Principles of Pharmacology
QUESTIONS AND ANSWERS WITH VERIFIED
SOLUTIONS 100% CORRECT

Pharmacokinetics is:


A. The effect the drug has on the body.
B. The adverse response of the drug on the body.
C. The effect the body has on the drug.

D. The clinical formulation of the drug - ANSWER C. The effect the body has on
the drug.


Absorption, distribution, metabolism, excretion


The ratio of minimum effective concentration (MEC) to minimum toxic
concentration (MTC) of a drug is the: - ANSWER therapeutic window


half life: - ANSWER the time it takes for the plasma concentration of the drug
to be reduced to half of its original value


Drug clearance formula - ANSWER rate of drug elimination / plasma
concentration of the drug


steady state - ANSWER when the rate of drug input equals the rate of drug
elimination

, Which of the following actions triggers a rise in membrane or action potential of a
cell?


A. Opening of the voltage gated sodium ions
B. Closure of voltage gated sodium ions
C. Opening of calcium ion channel

D. Opening of potassium voltage gated channels - ANSWER A. Opening of the
voltage gated sodium ions


Before stimulation, a cell has a slightly negative electric charge (compared with
ECF). Outside is more positively charged. When stimulus is encountered, sodium
ion channel opens and sodium rushes into the cell, causing depolarization (rise in
membrane/action potential)


The process by which a drug's activity is altered in order to prepare it for
excretion: - ANSWER biotransformation


The amino acid found in dairy products, fish, and eggs is tyrosine. The amino acid
from which tyrosine is made is: - ANSWER phenylalanine.


People take tyrosine to help manage depression, ADD, ADHD, narcolepsy, and to
improve alertness following sleep deprivation


The correct order of the transmission of a neurotransmitter is presynaptic
preparation followed by: - ANSWER arrival of action potential, release of
transmitter, receptor interaction, and the termination of transmitter action

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