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MICB 212 Immunology (Readings) Exam Study Guide 3 levels of defence - ANSWER1) anatomical and physiological -skin physical barrier, mucosal surfaces of the gut, respiratory urogenital and conjunctivae surfaces, stomach acid, lysozyme 2) innate immune response -phagocytosis, complement protei...

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  • October 30, 2024
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MICB 212 Immunology (Readings) Exam

Study Guide


3 levels of defence - ANSWER✔✔1) anatomical and physiological


-skin physical barrier,


mucosal surfaces of the gut, respiratory urogenital and conjunctivae surfaces,


stomach acid, lysozyme




2) innate immune response


-phagocytosis, complement protein activation


-limits spread and often resolves infection




3) adaptive immune response


-low to respond but specific to the particular pathogen,


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-involve antibody-mediated responses and cell-mediated responses.


two major cell populations in blood? - ANSWER✔✔1) erythrocytes (also called red blood cells or RBCs)

carry oxygen to the tissues,




2) leukocytes (also called white blood cells or WBCs) are the cells of the immune system.


Do ALL blood cells, including RBCs, arise from hematopoietic stem cells? - ANSWER✔✔YES including

RBCs


hematopoetic stem cells - ANSWER✔✔-self-renewing stem cells,




-found in the bone marrow, umbilical cord blood and in the blood (a very small number).


leukocytes - ANSWER✔✔myeloid and lymphoid cells


myeloid cells - ANSWER✔✔Participate in the INNATE immune response




-monocytes (that mature into macrophages),




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-mast cells,




-granulocytes (neutrophils, basophils, and eosinophils).


Lymphoid cells (aka lymphocytes) - ANSWER✔✔Participate in the ADAPTIVE immune response




-cytotoxic T cells (CTLs),




-T helper (Th) cells,




-T regulatory (Treg) cells,




-B cells.




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Natural killer cells (NK cells) - type of lymphoid cell that participates in innate responses. not be

discussed in MICB 202.


dendritic cells - ANSWER✔✔Dendritic cells - integral links between the innate and adaptive responses.




important cells for activating T cells & initiating adaptive immune response.




some come from myeloid others from lymphoid


location of immune system cells - ANSWER✔✔The cells of the immune system are found in the:




-blood circulatory system,




-lymphatic circulatory system,




-lymphoid organs.


Primary lymphoid organs - ANSWER✔✔site where lymphocytes mature

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