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PCB 3023 : Cell Biology Final Review Study Guide Solutions

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PCB 3023 : Cell Biology Final Review Study Guide Solutions If PAGE is carried out after subjecting the sample to SDS and beta-mercaptoethanol, then proteins will be separated on the basis of - ANSWER-Mass Which is the most abundant molecule in a bacterial cell? - ANSWER-Water Which of the foll...

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  • October 30, 2024
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FIRST PUBLISH OCTOBER 2024




PCB 3023 : Cell Biology Final Review

Study Guide Solutions


If PAGE is carried out after subjecting the sample to SDS and beta-mercaptoethanol, then proteins will be

separated on the basis of - ANSWER✔✔-Mass


Which is the most abundant molecule in a bacterial cell? - ANSWER✔✔-Water


Which of the following is true about the molecular properties of water? A) Water has a dipole moment.

B) Water can form hydrogen bonds with other water molecules. C) Water can form hydrogen bonds with

proteins, nucleic acids and phospholipids D) All choices are correct - ANSWER✔✔-All choices are correct


The major function of lysosome is - ANSWER✔✔-Degradation of macromolecules and organelles


Which of the following statements is true about interatomic bonds? - ANSWER✔✔-The covalent bond

between carbon and hydrogen is slightly polar


Nucleotides contain a __________-carbon sugar that is bonded to a _________ phosphate and a base -

ANSWER✔✔-five, charged


Gln is - ANSWER✔✔-An uncharged polar amino acid



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Which of the following is not true about fatty acids? - ANSWER✔✔-Cholesterol is a fatty acid


The bond between two sugar molecules formed via a dehydration process is called - ANSWER✔✔-

glycosidic bond


Which of the following statements is true about X-ray diffraction? - ANSWER✔✔-The structure obtained

from X-ray diffraction can contain crystal-packing artifacts


Proteins A and B bind to each other to form a complex, AB. Under equilibrium the concentrations of A, B

and AB are 10-2 M. The dissociation constant of this reaction is - ANSWER✔✔-10-2 M


Proteins can be denatured by a) Changing temperature b) Adding urea to solution c) Changing solvent d)

all choices are correct - ANSWER✔✔-All choices are correct


The dynamics of lipid bilayers depend on a) Temperature b) Lipid chemistry c) Cholesterol concentration

d) All choices are correct. - ANSWER✔✔-All choices are correct


Which of the following statements about entropy is true? - ANSWER✔✔-Entropy is a measure of system

multiplicity


A protein domain - ANSWER✔✔-can be disordered


Which of the following interactions are generally considered to be unfavorable? - ANSWER✔✔-

Interaction between Arg and Lys side chains at a pH of 7, assuming standard pKa values for Arg and Lys



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Van der Waals force is a kind of electromagnetic force - ANSWER✔✔-True


A person who carries blood group O can donate blood to a person who carries - ANSWER✔✔-Any of the

three blood groups, A, AB or O


In an alpha helix, residue i is hydrogen bonded to - ANSWER✔✔-Residue i+4 through its backbone


At physiological pH, phosphatidylserine has - ANSWER✔✔-a net negative charge


The permeability of a lipid bilayer for glucose is 10-8 cm/sec. Consider a cell whose glucose transporter is

knocked out. If it is placed in a solution that contains 1 mM glucose, how many glucose molecules will

enter the cell in 10 seconds? Assume that the cell contains no glucose and the surface area of its plasma

membrane is 5 μm2. - ANSWER✔✔-3000


Which is the following is true about the NaK pump? - ANSWER✔✔-It helps regulate cell volume


Ion channels cannot transport ions across membranes at rates faster than those predicted by Fick's law -

ANSWER✔✔-False


Proteins A, B and C bind to each other to form a complex, ABC. Under equilibrium the concentrations of

A, B, C and ABC are 10-2 M. The standard free energy of this reaction at T=300 K is - ANSWER✔✔--5.5

kcal/mol


Which of the following statements is true about biological reactions? - ANSWER✔✔-Some biological

reactions can occur without enzymes

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Assume that the kinetics of a phosphorylation reaction carried out by a kinase can be appropriately

described by the Michaelis-Menten relationship. Competitive inhibition of this kinase by a drug molecule

will - ANSWER✔✔-Alter the slope of the line in the Lineweaver-Burk plot, but not the maximum rate of

the reaction.


Which channel needs to be in the open state during the rising phase of an action potential? -

ANSWER✔✔-Voltage-gated Na+ channels


The action potential does not reverse direction on its own because - ANSWER✔✔-The voltage-gated Na+

channels cannot transition directly from inactive to open states


Myelination of axons - ANSWER✔✔-Increases the rate of nerve conduction


Neurotransmitters that open Cl- channels in the post-synaptic cell membrane - ANSWER✔✔-Produce a

similar effect as neurotransmitters that open K+ channels in the post-synaptic cell membrane


The microvilli of specialized epithelia are structurally composed of - ANSWER✔✔-Plasma membrane

covering an actin bundle


Which of the following could be affected by a mutation in the actin protein? I. Muscle contraction II. Cell

locomotion III. Mitosis IV. Cell shape - ANSWER✔✔-I, II, III and IV


Which of the following statement is true about intermediate filaments? - ANSWER✔✔-Intermediate

filaments play a key role in the formation of cell-cell junctions.



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