WGU D116 ADVANCED PHARMACOLOGY OA
EXAM 2024/2025 PRACTICE QUESTIONS AND
ANSWERS GRADED A+
A patient asks his provider to explain what drug tolerance means.
The provider responds by telling the patient that when tolerance occurs, it means the patient
__________.
may need increased amounts of the drug over time
When tolerance develops, a dose increase may be needed because a decreased response may occur
with prolonged use
A group of nursing students asks a nurse to explain the blood-brain barrier.
The nurse would be correct to say that the blood-brain barrier __________.
Prevents some potentially toxic substances from crossing into the central nervous system
Infants are more sensitive to CNS drugs and require lower doses
Prevents highly ionized and protein-bound drugs from entering
Allows lipid-soluble drugs drugs and drugs that use specific transport systems to enter
A pregnant patient is in premature labor.
,WGU D116 ADVANCED PHARMACOLOGY OA EXAM 2024/2025
Which class of drug will she be given?
Beta 2 agonist (helper)
Part of the peripheral adrenergic receptor subtypes (epi/norepi)
Beta2 agonists cause relaxation of the uterine muscles, slowing or stopping the contractions that
precipitate labor
Beta2 ANTagonist would increase constriction of the uterine muscles
What type of drug class has effects on the heart and arterioles?
Alpha1 agonist
Anticcholinergic drugs are given for what effects?
Urinary and GI tracts
They do not affect the urine muscles
A nurse is explaining the activation of beta-2 receptors to nursing students during a clinical rotation at
the hospital.
Which statement by a student demonstrates a need for further teaching?
"Beta2 activation results in contraction of the uterine muscles"
,WGU D116 ADVANCED PHARMACOLOGY OA EXAM 2024/2025
Beta2 activation DOES result in vasodilation of skeletal muscles, bronchodilation, and glycogenolysis,
and RELAXATION of uterine muscles
A provider is teaching a patient about a medication that alters the sympathetic nervous system
functions. To evaluate understanding, the provider asks the patient to describe which functions the
sympathetic nervous system regulates.
Which answer indicates the need for further teaching?
"The digestive functions of the body"
All apart of the sympathetic nervous system:
1. fight or flight
2. cardiovascular system
3. body temperature
A patient is experiencing toxic side effects from atropine, including delirium and hallucinations.
Which medication will the provider ask the nurse to administer?
Physostigmine (Mestinon, Regonol)
Drug of choice for treating poisoning from atropine and other drugs that cause muscarinic blockage ie:
atropine (Muscarinic Antagonist)
What drug is used to treat Alzheimer's Disease?
Donepezil
, WGU D116 ADVANCED PHARMACOLOGY OA EXAM 2024/2025
A patient who has myasthenia gravis will be taking neostigmine.
What should the nurse emphasize when teaching this patient about the medication?
Take a supplementary dose before exercise
You have ordered pilocarpine. You understand that the drug stimulates muscarinic receptors.
Which action would you expect the drug to have?
Lowering of intraocular pressure in pts with glaucoma
Also used to treat dry mouth because it increases salivary glands "Rest and digest"
Muscarinic agents are related to parasympathetic response
You are teaching a nursing student about the two classes of adrenergic agonist drugs.
Which statement by the nursing student indicates understanding of the teaching?
Catecholamines often require continuous infusion to be effective
Catecholamines undergo rapid degradtion by monoamine oxidase MAO and COMT. Brief duration of
action and continuous IV to be effective
They DO NOT cross the BBB, noncatecholamines do
Noncatecholamines can be given orally but catehcholamines can not
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