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USMLE Step 1 Rapid Review Study Guide Solutions
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USMLE Step 1 Rapid Review Study Guide Solutions abdominal pain, ascites, hepatomegaly - ANSWER-Budd-Chiari syndrome Familial hypercholesterolemia - ANSWER-achilles tendon xanthoma adrenal hemorrhage, hypotension, DIC - ANSWER-Waterhouse-Friderichsen syndrome biochemistry of Marfan's syndrome -...

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  • October 31, 2024
  • 66
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • usmle step 1 rapid review study guide solutions

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©EMILLECT 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




USMLE Step 1 Rapid Review Study Guide

Solutions


abdominal pain, ascites, hepatomegaly - ANSWER✔✔-Budd-Chiari syndrome


Familial hypercholesterolemia - ANSWER✔✔-achilles tendon xanthoma


adrenal hemorrhage, hypotension, DIC - ANSWER✔✔-Waterhouse-Friderichsen syndrome


biochemistry of Marfan's syndrome - ANSWER✔✔-fibrillin defect


posthepatic venous thrombosis - ANSWER✔✔-Budd-Chiari syndrome


Familial hypercholesterolemia biochemistry - ANSWER✔✔-decrease in LDL receptor signaling


Waterhouse-Friderichsen syndrome cause - ANSWER✔✔-meningococcemia


arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - ANSWER✔✔-Marfan's syndrome


Athlete with polycythemia - ANSWER✔✔-EPO injection


Pott's disease - ANSWER✔✔-vertebral TB




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, ©EMILLECT 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




Pott's disease clinical presentation - ANSWER✔✔-back pain, fever, night sweats, weight loss


Sarcoidosis main histological presentation - ANSWER✔✔-noncaseating granuloma


bilateral hilar adenopathy + uveitis - ANSWER✔✔-sarcoidosis


Osteogenesis imperfecta - ANSWER✔✔-type I collagen defect


Blue sclera indicate what? - ANSWER✔✔-osteogenesis imperfecta


Burton's line indicates what? - ANSWER✔✔-lead poisoning


Burton's line - ANSWER✔✔-bluish line on gingiva


Paget's disease of the bone biochemistry - ANSWER✔✔-increase in osteoblastic and osteoclastic activity


bone pain, bone enlargement, arthritis - ANSWER✔✔-Paget's disease of the bone


bounding pulses, diastolic heart murmur, head bobbing - ANSWER✔✔-aortic regurgitation


butterfly facial rash, Raynaud's phenomenon in a young female - ANSWER✔✔-SLE


Neurofibromatosis type I associated with what malignancies - ANSWER✔✔-pheochromocytoma, optic

gliomas


cafe-au-lait spots and Lisch nodules - ANSWER✔✔-Neurofibromatosis type I


Page 2/66

, ©EMILLECT 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




Lisch nodules - ANSWER✔✔-iris hemartoma


McCune-Albright syndrome biochemistry - ANSWER✔✔-mosaic continuous activation of stimulatory G

protein


cafe-au-lait spots, polyostotic fibrous dysplasia, precocious puberty, multiple endocrine abnormalities -

ANSWER✔✔-McCune-Albright syndrome


Duchenne's muscular dystrophy - ANSWER✔✔-X-linked recessive deletion of dystrophin gene


Calf pseduohypertrophy - ANSWER✔✔-Duchenne's muscular dystrophy


clinical sign of Tay-Sach's, Niemann-Pick, or central retinal artery occlusion - ANSWER✔✔-Cherry-red

spot on macula


ganglioside accumulation - ANSWER✔✔-Tay-Sach's


sphingomyelin accumulation - ANSWER✔✔-Niemann-Pick disease


Stable angina - ANSWER✔✔-with moderate exercise


Unstable angina - ANSWER✔✔-with minimal exertion


Angina - ANSWER✔✔-chest pain on exertion




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, ©EMILLECT 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED

FIRST PUBLISH OCTOBER 2024




autoimmune-mediated post-MI fibrinous pericarditis 1-12 weeks after acute episode - ANSWER✔✔-

Dressler syndrome


Chest pain, pericardial effusion, friction rub, persistent fever following MI 1-12 weeks after -

ANSWER✔✔-Dressler's syndrome


Gowers' sign associated with what disease? - ANSWER✔✔-Duchenne muscular dystrophy


Gower's sign definition - ANSWER✔✔-child uses arms to stand up from squat


"Slapped cheeks" - ANSWER✔✔-erythema infectiosum/fifth disease


Erythema infectiosum/fifth disease - ANSWER✔✔-parvovirus B19


child with fever later develops red rash on face that spreads to body - ANSWER✔✔-erythema

infectiosum/fifth disease


autosomal-dominant CAG repeat expansion - ANSWER✔✔-Huntington's disease


chorea, dementia, caudate degeneration - ANSWER✔✔-Huntington's disease


muscle glycogen phosphorylase deficiency - ANSWER✔✔-McArdle's syndrome


chronic exercise intolerance with myalgia, fatigue, painful cramps, myoglobinuria - ANSWER✔✔-

McArdle's disease



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