100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved $13.49   Add to cart

Exam (elaborations)

MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved

 6 views  0 purchase
  • Course
  • MDSC
  • Institution
  • MDSC

MDSC 321 Midterm 1 Exam Questions and Answers 100% Solved What makes a good vaccine? - Variolation or Inoculation (Safety) Vaccination (Cost) Effectiveness Type of Immunity Vaccine Production - Dried up small pox scabs, ship live cows to make the vaccine, own farms for vaccine production, in...

[Show more]

Preview 4 out of 39  pages

  • November 1, 2024
  • 39
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • MDSC
  • MDSC
avatar-seller
NinjaNerd
©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
MDSC 321 Midterm 1 Exam Questions

and Answers 100% Solved


What makes a good vaccine? - ✔✔Variolation or Inoculation (Safety)

Vaccination (Cost)

Effectiveness

Type of Immunity

Vaccine Production - ✔✔Dried up small pox scabs, ship live cows to make

the vaccine, own farms for vaccine production, infect egg with virus to

make the vaccine, DNA vaccines take a gene that codes for one of the

proteins to inject with the piece of DNA. Can't control where gene goes.

Vaccine Composition (Live Attenuated) - ✔✔Weakened or less virulent

pathogen

Actually infect the host

Robust immune response

Long lasting memory

Ex. Measles, Mumps

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Vaccine Composition (Killed) - ✔✔Whole killed pathogens (lots of potential

antigens)

Unable to infect the host

Weaker, short lived immunity

Often requires multiple boosters

Ex. Polio, Influenza

Vaccine Composition (Subunit or Toxoid) - ✔✔Specific molecules isolated

from a pathogen

Unable to infect the host

Weaker, short lived humoral (Ab) immunity

Often requires multiple boosters

Ex. Diphtheria, Tetanus

How is vaccination influenced by public perception? - ✔✔Autism, falsified

data, fraudulent. Not immunized you will get the disease. Herd immunity

threshold for a number of infectious diseases such as measles, diphtheria,

mumps etc.

Do we need to be vaccinated against everything? - ✔✔Effect of vaccinating

for one disease on other disease.

- Chicken pox and shingles are cause by the same virus

,©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Chicken pox significant decrease but increase in shingles people are not as

exposed to chicken pox and your immune system gets lazy

How has our world changed? - ✔✔Smallpox is the only disease eradicated

in history of humans by world wide vaccination effort. Spend $1 on a

vaccine and save $30

Are antibodies a silver bullet drug? - ✔✔Stick to a target and mutualize

each other so then the disease cannot stick to your cells and infect you.

Antibodies - Therapeutics - ✔✔-Antibodies are a protein produced by the

immune system that specifically recognizes target molecules

-Antibody therapeutics bind and neutralize targets, activate cells, kill cells,

and modulate immunity

-Represents the first immune treatments (>100 years ago)

- More than 30 licenced monoclonal Ab are sold in the US for treatment of

human disease

-8 /20 best selling biotech drugs were antibodies

-Currently used to treat cancers (colon, brain, lymphoma, leukemia, breast)

- Treat autoimmunity (lupus, arthritis, MS, asthma, IBD, Crohn's, diabetes)

- Treat infections (Hep B, HIV, sepsis, rabies, tetanus, C.difficile, anthrax)

- Prevent transplant rejection

, ©NINJANERD 2024/2025. YEAR PUBLISHED 2024.
Antibodies AB structures developed from non-rodent/non-primate species -

✔✔Not all anitbodies are the same, structural differences confer functional

differences

IgM- sticks to target

IgD-

IgG-making when you vaccinate someone

IgE-allergies

IgA- GI tract keeps gut lining from getting effected

Antibodies - Structure - ✔✔Bispecific - could recognize two things are the

same time

"Smart Drugs"- Immunotoxins/ Antibody Drug Conjugates (ADC) -

✔✔Direct a drug to a specific target recognized by the antibody.

Conventional Chemotherapy: recognize the tumor cell, place the drug and

kill it

Infectious Disease - ✔✔Worldwide, 1 in 3 deaths is attributable to

infectious disease

Vast majority of these deaths are preventable by vaccine

Making progress but one of the biggest threats is emerging and re-

emerging disease

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller NinjaNerd. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $13.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67096 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$13.49
  • (0)
  Add to cart