SCN1111 Health Science Sem 1 Exam Questions and Answers 100% Solved
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Course
SCN1111
Institution
SCN1111
SCN1111 Health Science Sem 1 Exam
Questions and Answers 100% Solved
medial - middle/towards middle
lateral - away from middle
intermediate - between medial and lateral structure
proximal - close to body part
distal - far from body part
superficial - toward surface
deep - away from surface
...
autocrines: chemicals that exert effects on same cells that secrete them
paracrines: locally acting chemicals that affect cells (not those that secrete
them)
(autocrines and paracrines are local & not part of endocrine system)
direct gene activation mechanism (steroid hormones) - ✔✔steroid
hormones diffuse into target cell and bind with intracellular receptors.
receptor hormone complex enters the nucleus, binds to specific region of
DNA, prompts DNA to produce mRNA. mRNA directs protein synthesis,
promotes metabolic activities, and prepares proteins for export from cell.
PIP2- signalling mechanism (amine hormones) - ✔✔involves G protein and
membrane bound effector phospholipase C. Phospholipase C splits PIP2
into 2 second messengers - diacylglycerol (DAG) and inositol triphosphate
(IP3). DAG activates protein kinase: IP3 causes Ca release. calcium ions
act as second messengers and alter enzyme activity
cAMP signalling mechanism (amine hormones) - ✔✔hormone binds to
receptor, activates G protein, G protein activates adenylate cyclase.
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