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CLINICAL INTEGRATION 2 STUDENT QUESTIONS - EXAM 1 PREVIOUS YEARS QUESTIONS WITH COMPLETE ANSWERS.
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CLINICAL INTEGRATION 2 STUDENT QUESTIONS - EXAM 1 PREVIOUS YEARS QUESTIONS WITH COMPLETE ANSWERS.
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CLINICAL INTEGRATION 2 STUDENTQUESTIONS - EXAM 1 PREVIOUS
YEARS QUESTIONS WITH COMPLETE
ANSWERS
An vv85 vvyear vvold vvsmoker vvpresents vvwith vvhypotension vvand vvsudden, vvsevere
vvabdominal vvpain. vvPhysical vvexam vvreveals vva vvpulsatile, vvnon-tender vvmass vvbelow
vvthe vvumbilicus. vvWhat vvis vvthe vvlikely vvdiagnosis?
A vv- vvRuptured vvAbdominal vvAortic vvAneurysm
B vv- vvMarfan's vvsyndrome
C vv- vvRaynaud's vvPhenomenon
D vv- vvPompe vvDisease
E vv- vvHereditary vvSpherocytosis vv- vvAnswer vvA vv- vvRuptured vvAbdominal vvAortic
vvAneurysm
A vv34 vvyear vvold vvman vvvisits vvhis vvPCP vvwith vvcomplaints vvof vvfrequent vvcramping
vvof vvhis vvlegs vvand vvhands vvat vvhis vvjob vvin vvconstruction. vvHe vvhas vvsmoked vva
vvpack vvof vvcigarettes vvevery vvday vvfor vvthe vvpast vv10 vvyears. vvThe vvphysician
vvnotices vvswelling vvaround vva vvvein vvin vvhis vvleg vvand vvdecides vvto vvtake vva vvbiopsy
vvof vvit, vvshowing vva vvthrombus vvwithout vvinvolvement vvof vvstructures vvof vvthe vvvessel
vvwall. vvWhat vvis vvthe vvmost vvlikely vvdiagnosis?
A) vvRaynaud's vvphenomenon
B) vvTakayasu's vvarteritis
C) vvBuerger's vvdisease
D) vvAV vvfistula
E) vvGiant vvcell vvarteritis vv- vvAnswer vvC) vvBuerger's vvdisease
A vv72 vvyear vvold vvmale vvpresents vvto vvthe vvED vvwith vvchest vvpain. vvAttached vvare
vvthe vvfindings vvon vvthe vvCT vvangiogram vvof vvhis vvdescending vvaorta. vvIt vvshows vva
vvlarge vvpenetrating vvaortic vvulcer vvabove vvthe vvdiaphragm. vvWhich vvof vvthe
vvfollowing vvis vva vvmajor vvcomplication vvof vvboth vvpenetrating vvulcers vvand
vvintramural vvhematomas?
A vv- vvArteriovenous vvfistula
B vv- vvAortic vvrupture
,C vv- vvPulmonary vvhypertension
D vv- vvVenous vvthromboembolic vvdisease
E vv- vvDeep vvvein vvthrombosis vv- vvAnswer vvB vv- vvAortic vvrupture
A vv60-year-old vvmale vvpatient vvcomplains vvof vvshoulder vvpain, vvvisual vvdisturbances
vvand vva vvheadache. vvPhysical vvand vvLaboratory vvtests vvreveal vvlow vvgrade vvfever,
vvscalp-tenderness vvand vvsignificantly vvelevated vvC-reactive vvprotein. vvDiagnosis vvis
vvconfirmed vvvia vvhistologic vvexamination vvof vvarterial vvtissue, vvshowing vvinfiltration
vvof vv"giant vvcells" vvin vvthe vvvascular vvwall. vvWhich vvof vvthe vvfollowing vvis vvthe vvbest
vvcourse vvof vvtreatment vvfor vvthe vvpatient?
A) vvCalcium vvchannel vvblockers
B) vvHigh vvdose vvcorticosteroids
C) vvTranscatheter vvembolization
D) vvCorticosteroids vvand vvsurgical vvrevascularization
E) vvTobacco vvabstinence
F) vvLow vvdose vvcorticosteroids vvthen vvincrease vvdose vvover vvtime vv- vvAnswer vvB)
vvHigh vvdose vvcorticosteroids
A vv27 vvyear vvold vvAsian vvfemale vvpresents vvto vvthe vvclinic vvwith vvcoronary vvischemia
vvand vvcongestive vvheart vvfailure. vvPhysical vvfindings vvinclude vvbruits vvover vvthe
vvaorta vvwith vvdiminished vvbrachial vvpulses. vvWhat vvis vvthe vvmost vvappropriate vvfirst-
line vvtreatment vvstep?
A) vvFolate
B) vvGentamicin
C) vvCorticosteroids
D) vvZanamivir
E) vvAmlodipine vv- vvAnswer vvC) vvCorticosteroids
Darla vvcomes vvinto vvthe vvemergency vvdepartment vvyelling vvand vvrunning vvaround.
vvShe vvthrows vvup vvall vvover vvthe vvdoctor vvand vvsuddenly vvloses vvconsciousness.
vvQuick vvtesting vvshows vvthat vvshe vvhas vvan vvabundant vvamount vvof vvcocaine vvin
vvher vvsystem. vvA vvCT vvscan vvconfirms vvDarla vvhas vvan vvaortic vvdissection vvand
vvneeds vvimmediate vvcare. vvThe vvscan vvshows vva vvcomplete vvaortic vvdissection.
vvWhat vvtype vvof vvdissection vvdoes vvDarla vvhave vv?
A) vvType vvI
B) vvType vvIII
C) vvType vvA
D) vvType vvII
E) vvType vvB vv- vvAnswer vvA) vvType vvI
A vv60 vvyear vvold vvmale vvpresents vvto vvthe vvoffice vvwith vvcomplaints vvof vvsevere vvcalf
vvpain vvwhile vvcompleting vvhis vvdaily vvwalk vvfor vvthe vvpast vv3 vvweeks. vvHe vvstates
vvthat vvthe vvcalf vvpain vvis vvalleviated vvwhen vvhe vvreturns vvhome vvand vvrests. vvHe
,vvalso vvfeels vvas vvthough vvhe vvis vvlosing vvhair vvon vvhis vvlegs vvand vvtoes vvdespite vvno
vvchange vvin vvdiet vvor vvtoiletries. vvUpon vvphysical vvexam, vvit vvis vvnoted vvthat vvthe
vvskin vvto vvhis vvlower vvextremities vvare vvshiny vvand vvhave vva vvcyanotic vvtint. vvThe
vvmost vvlikely vvdiagnosis vvis:
1) vvPeripheral vvArtery vvDisease vv(PAD)
2) vvAortic vvAneurysm
3) vvAortic vvDissection
4) vvGiant-cell vvArteritis
5) vvTakayasu's vvArteritis vv- vvAnswer vv1) vvPeripheral vvArtery vvDisease vv(PAD)
A vv40 vvyear vvold vvfemale vvpresents vvto vvher vvPCP vvcomplaining vvof vvrecurrent
vvepisodes vvof vvpallor vvfollowed vvby vvcyanosis vvand vvthen vverythema vvof vvher
vvfingers vvand vvtoes. vvShe vvstates vvthat vvshe vvexperiences vvthese vvsymptoms
vvparticularly vvin vvcolder vvtemperatures. vvThe vvphysician vvprescribes vva vvcalcium
vvchannel vvblocker vvto vvreduce vvthe vvfrequency vvand vvseverity vvof vvher vvsymptoms.
vvWhat vvis vvthe vvmost vvlikely vvdiagnosis vvfor vvthis vvpatient?
1) vvBuerger's vvdisease
2) vvRaynaud's vvphenomenon
3) vvGiant vvcell vvarteritis
4) vvTakayasu's vvarteritis
5) vvArteriovenous vvfistula vv- vvAnswer vv2) vvRaynaud's vvphenomenon
A vv5-year-old vvfemale vvpresents vvwith vvretinoblastoma vvand vvis vvconfirmed vvto vvhave
vvinherited vva vvmutant vvRb1 vvallele. vvAlthough vvher vvfather vvwasn't vvaffected, vvhis
vvown vvmother vvwas. vvFamily vvhistory vvis vvinsignificant vvon vvher vvmother's vvside.
vvWhat vvis vvthe vvmost vvlikely vvreason vvher vvfather vvnever vvexhibited vva vvdisease
vvphenotype?
A. vvThe vvfather vvdid vvnot vvpossess vva vvdisease-causing vvgenotype
B. vvVariable vvexpression
C. vvGermline vvmosaicism
D. vvIncomplete vvpenetrance
E. vvLocus vvheterogeneity vv- vvAnswer vvD. vvIncomplete vvpenetrance
A vv6-year-old vvpatient vvis vvdiagnosed vvwith vva vvmutation vvin vvthe vvCFTR vvgene. vvAs
vvthe vvdisease vvprogresses vvwhat vvphenotype vvwould vvnot vvpresent vvin vvthe vvpatient?
A. vvFibrotic vvlesions vvin vvthe vvpancreas
B. vvCystic vvmedial vvnecrosis
C. vvInability vvto vvreabsorb vvchloride vvfrom vvthe vvlumen vvof vvsweat vvglands
D. vvPulmonary vvfibrosis
E. vvChronic vvmalabsorption vvof vvnutrients vv- vvAnswer vvB. vvCystic vvmedial vvnecrosis
, The vv3-year-old vvchild vvof vva vvyoung vvcouple vvhas vvjust vvbeen vvdiagnosed vvwith
vvcystic vvfibrosis, vvan vvautosomal vvrecessive vvdisorder. vvRecently vvit vvhas vvcome vvto
vvlight vvthat vvthe vvcouple vvshares vvfamilial vvlineage vvand vvare vvtechnically vvcousins.
vvWhat vvphenomena vvbest vvexplains vvthe vvincreased vvrisk vvof vvthis vvautosomal
vvrecessive vvdisorder vvin vvtheir vvchild?
A. vvVariable vvexpression
B. vvAllelic vvheterogeneity
C. vvConsanguinity
D. vvLocus vvheterogeneity
E. vvMarfan vvsyndrome vv- vvAnswer vvC. vvConsanguinity
A vv35-year-old vvpatient vvis vvdiagnosed vvwith vva vvmutation vvin vvthe vvNF1 vvgene.
vvWhat vvclinical vvfeatures vvwould vvpresent vvin vvthis vvpatient?
A) vvCafé-au-lait vvspots vv& vvLisch vvnodules
B) vvMyopia vv& vvarachnodactyly
C) vvAspiration vvpneumonia
D) vvLong vvlimbs vv& vvnarrow vvface
E) vvBronchial vvinfection vv- vvAnswer vvA) vvCafé-au-lait vvspots vv& vvLisch vvnodules
A vvmarried vvcouple vvdecides vvthat vvthey vvwant vvto vvstart vvto vvtry vvand vvhave
vvchildren; vvbefore vvbeginning vvto vvtry vvthey vvdecide vvto vvconduct vva vvgenetic
vvscreening vvas vvthe vvman vvhas vvconcerns vvas vvhis vvfamily vvhas vva vvhistory vvof
vvTay-Sachs. vvThe vvcounselor vvconfirms vvto vvthe vvman vvthat vvhe vvand, vvin vvfact, vvhis
vvwife vvare vvboth vvcarriers vvfor vvTay-Sachs. vvThe vvcouple vvis vvnow vvconsidered vvfor
vvthe vvrisk vvof vvhaving vva vvchild vvdominant vvfor vvTay-Sachs, vvwhat vvis vvthe
vvrecurrence vvrisk vvof vvTay-Sachs vvdisease vvin vvthis vvsituation?
A. vv50%
B. vv25%
C. vv33%
D. vv100%
E. vv0% vv- vvAnswer vvB. vv25%
Postaxial vvpolydactyly, vvthe vvpresence vvof vvan vvextra vvdigit vvnext vvto vvthe vvfifth vvdigit,
vvis vvinherited vvas vvan vvautosomal vvdominant vvtrait. vvA vvnewborn vvmale vvis vvfound
vvto vvhave vvsix vvdigits vvon vvhis vvhands. vvThe vvfather vvis vva vvhomozygous,
vvunaffected vvparent. vvWhich vvof vvthe vvfollowing vvcases vvis vva vvpossible vvexplanation
vvas vvto vvwhy vvthe vvnewborn vvhas vvpostaxial vvpolydactyly?
a. vvThe vvmother vvof vvthe vvchild vvis vvheterozygous vvand vvaffected vvfor vvpostaxial
vvpolydactyly
b. vvThe vvmother vvof vvthe vvchild vvis vvheterozygous vvand vvunaffected vvfor vvpostaxial
vvpolydactyly
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