Exam (elaborations)
ACNP Endocrine - Questions And Proper Solutions
- Course
- Institution
ACNP Endocrine - Questions And Proper Solutions
[Show more]
Content preview
ACNP Endocrine - Questions And Proper SolutionsDiabetes Type 1 Right Ans - strongly associated with presence of human
leukocyte antigens and a genetic predisposition
Diabetes Type 1 Right Ans - islet cell antibodies found in approximately
90% of patients within first year of diagnosis
Diabetes Type 1 Right Ans - ketone development usually occurs. often have
recent weight loss at time of diagnosis
Diabetes Type 1 Right Ans - believed to be the result of an infectious or
toxic environmental insult to pancreatic B cells of genetically predisposed
persons
Common Lab findings in Diabetes Right Ans - Random plasma glucose >
200
serum fasting glucose >126 on 2 separate ocassions
Ketonemia, ketonuria or both (type 1 only)
increased BUN/ Cr
increased Hgb A1c
Insulin therapy for DM1 Right Ans - Initiate with 0.5 u/kg/day, giving 2/3
of the dose in the A< and the remaining 1/3 in the evening
- Conventional: AM dose is 2/3 NPH and 1/3 Regular; PM dose is 1/2 NPH and
1/2 regular
- Intensive: reduce or omit the PM dose and add a portion at bedtime
Diabetes Type 2 Right Ans - circulating insulin exists enough to prevent
ketoacidosis, but is inadequate to meet the patient's insulin needs
Diabetes Type 2 Right Ans - caused by either tissue insensitivity to insulin
or an insulin secretory defect resulting in resistance and/or impaired insulin
production
Syndrome X Right Ans - obestiy, HTN, abnormal lipid profiles (low HDLs
and high triglycerides)
Metabolic Syndrome Right Ans - YES to any 3...
, 1. Waist circumference >40 in (101.6 cm) in men, and >35 in (88.9 cm) in
women
2. BP > 130/85
3. Triglycerides > 150
4. FBG > 100
5. HDL < 40 in men and < 50 in women
Diabetes Type 2 Right Ans - insidious onset of hyperglycemia
Diabetes Type 2 Right Ans - recurrent vaginitis is often first symptom in
women, peripheral neuropathies, blurred vision or vision changes in 1 year,
chronic skin infections including pruritus
Diabetes Type 2 Right Ans - Same labs/diagnostics as Type 1 except NO
ketones in blood or urine
Diabetes Type 2 Treatment Right Ans - Begin with weight control for
obese, dietary treatment, exercise, early use of oral antidiabetics
Sulfonylureas Right Ans - most widely prescribed
stimulate the pancreas to release more insulin
Sulfonylureas Right Ans - Glipizide, Glyburide, Glimepiride
"G" group
Biguanides Right Ans - Standard of care for DM2 diagnoses
Good adjunct but can be used alone, especially for obese patients
Increase insulin sensitivity
Metformin Right Ans - Biguanide with common side effect of lactic acidosis.
Patient may present with muscle pain.
Alpha-glucosidase inhibitors Right Ans - bind to disaccharidases more
readily than sucrose, so less glucose is absorbed by the gut
Alpha-glucosidase inhibitors Right Ans - Acarbose (Precose), Miglitol
(Glyset)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller LeCrae. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now