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Clayton's Basic Pharmacology for Nurses: Chapter 2 Questions With Complete Solutions
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Clayton's Basic Pharmacology for Nurses: Chapter 2 Questions With Complete Solutions
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Clayton's Basic Pharmacology for Nurses: Chapter 2Questions With Complete Solutions
3 routes of drug administration: Correct Answer - enteral
- parenteral
- percutaneous
a drug only forms a bond with a receptor if: Correct Answer -
the drug and the receptor have similar shapes
- the drug has a chemical affinity for the receptor
a patient with renal failure often has a ___________________ in
the action and duration of a drug if the dosage and frequency of
administration are not adjusted to allow for the patient's reduced
renal function Correct Answer increase
absorption of a drug is slowest when administered this way
Correct Answer subcutaneous injection
after administration, all drugs go through 5 stages: Correct
Answer - liberation
- absorption
- distribution
- metabolism
- excretion
ampicillin + gentamicin = ampicillin inactivates gentamicin
Correct Answer incompatibility
an injury resulting from medical intervention related to a drug;
medication errors Correct Answer adverse drug events (ADE)
, any noxious, unintended and undesired effect of a drug which
occurs at dosages used in humans for prophylaxis, diagnosis, or
therapy Correct Answer adverse drug reaction (ADR)
aspirin + codeine = much greater analgesic effect Correct
Answer synergistic effect
classes of medication which account for the largest number of
ADR's Correct Answer - antibiotics
- cardiovascular medicines
- cancer chemotherapy agents
- analgesics
- antiinflammatory agents
common drugs that bind to enzymes and increase the
metabolism of other drugs: Correct Answer - phenobarbital
- carbamazepine
- rifampin
- phenytoin
drug interactions are elicited in two ways: Correct Answer - by
agents that when combined increase the actions of one or both
drugs
- by agents that when combined decrease the effectiveness of
one or both drugs
drug interactions that cause a change in distribution usually
affect the ____________________ of a drug to an inactive site
Correct Answer binding
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