100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
Bio 2b03 exam review Questions and Answers $12.49   Add to cart
Quickly navigate to
Preview
  2.  
  3. Prep Tests
  4.  
  5. Prep Tests

Exam (elaborations)

Bio 2b03 exam review Questions and Answers
 0 view  0 purchase
  • Course
  • Prep Tests
  • Institution
  • Prep Tests

Bio 2b03 exam review Questions and Answers is the RER dynamic or stationary? - ANSWER-dynamic what is the function of the RER? - ANSWER-co-translational transport, protein modification, formation of vesicles that will transport proteins from ER to Golgi what is the function of the SER? - ANSWE...

[Show more]

Preview 3 out of 21  pages

Document information

  • November 3, 2024
  • 21
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • bio 2b03 exam review questions and answers

Written for

  • Prep Tests
  • Prep Tests

Seller

avatar-seller
KaylinHoffman

Content preview

Copyright © KAYLIN 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH NOVEMBER, 2024




Bio 2b03 exam review Questions and

Answers


is the RER dynamic or stationary? - ANSWER✔✔-dynamic


what is the function of the RER? - ANSWER✔✔-co-translational transport, protein modification,

formation of vesicles that will transport proteins from ER to Golgi


what is the function of the SER? - ANSWER✔✔-fatty acid and phospholipid synthesis, carbohydrate

metabolism, regulate Ca2+ conc in the cytosol


what are the post translational modifications in the ER? - ANSWER✔✔-- glycosylation


- protein folding


- disulphide bond formation


- proteolytic cleavage


do modifications to proteins embedded in the ER membrane occur in the luminal portion or the

transmembrane domain or the cytosolic portion? - ANSWER✔✔-luminal


this protein modification is important for proteins that mediate cell interactions with the extracellular

matrix and for receptor-ligand recognition - ANSWER✔✔-glycosylation


this protein modification is common on proteins that are secreted from the cell and proteins embedded

in the cell membrane - ANSWER✔✔-glycosylation


what is the most common form of glycosylation? - ANSWER✔✔-N-linked

Copyright ©Stuvia International BV 2010-2024 Page 1/21

,Copyright © KAYLIN 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH NOVEMBER, 2024


N-linked glycosylation adds a polysaccharide to which group of which amino acid? - ANSWER✔✔-NH2

group of the R-group of asparagine


these proteins recognize modified proteins and assist in protein folding in a similar way as chaperones -

ANSWER✔✔-lectins


what are the two types of lectins? - ANSWER✔✔-calnexin and calreticulin


where is calnexin found? - ANSWER✔✔-ER membrane


what is BiP? mention 3 functions - ANSWER✔✔-- ER-resident HSP70 chaperone


- transfers proteins from ER through the translocon by binding to proteins as soon as they appear on the

luminal side of the membrane during co-translational transport


- initiate unfolded protein response in the ER


what are the co-chaperones of BiP? - ANSWER✔✔-Hsp40 and NEF


is cytoplasm a reducing or an oxidizing environment? - ANSWER✔✔-reducing


is ER a reducing or an oxidizing environment? - ANSWER✔✔-oxidizing


does disulphide bond formation occur in reducing or oxidizing environment? - ANSWER✔✔-oxidizing


this protein is one of many proteins secreted into the intestine where it aids in the digestion of RNA by

cleaving it into small pieces - ANSWER✔✔-RNAse A


what is the protein that resides in the ER that promotes oxidation? - ANSWER✔✔-protein disulphide

isomerase (PDI)


does proteolytic cleavage in the ER happen in the lumen or the cytosol? - ANSWER✔✔-lumen


Copyright ©Stuvia International BV 2010-2024 Page 2/21

, Copyright © KAYLIN 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED FIRST PUBLISH NOVEMBER, 2024


what is the N-terminal signal sequence of type I integral proteins cleaved by? - ANSWER✔✔-signal

peptidase


what are the two responses of the unfolded protein response (UPR)? - ANSWER✔✔-1. restore normal

cell function by slowing down new protein translation or removing unfolded proteins from the ER for

degradation through ubiquitylation


2. increase production of chaperones


what are the proteins essential to UPR? - ANSWER✔✔-BiP and Ire1


this protein is involved in the UPR and functions as a chaperone to assist in proper folding and prevent

aggregation of misfolded proteins - ANSWER✔✔-BiP


this is a transmembrane protein that is involved in the UPR - ANSWER✔✔-Ire1


Ire1 endonuclease specifically targets which gene's mRNA? - ANSWER✔✔-Hac1


what does unspliced Hac1 do? - ANSWER✔✔-inhibit translation


this protein is a transcription factor that activates transcription of several genes including the genes that

code for BiP, lectins, PDI, and signal peptidases - ANSWER✔✔-Hac1


where is the Hac1 protein transported to? - ANSWER✔✔-nucleus


moving from the ER towards the cell membrane - ANSWER✔✔-anterograde


moving from the cell membrane towards the ER - ANSWER✔✔-retrograde


what is pulse-chase labeling? - ANSWER✔✔-tags proteins for only a brief period of time, so that only

some proteins are labeled



Copyright ©Stuvia International BV 2010-2024 Page 3/21

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller KaylinHoffman. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

84146 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.49
  • (0)
  Add to cart