PHMY 610 ARBOVIRUSES & HEMORRHAGIC FEVERS
EXAM QUESTIONS AND ANSWERS
this is an agent that carries and transmits an infectious pathogen to/into another
living organism
disease vector
what are examples of disease vectors
mosquitos, ticks, flies, rodents, fleas
this is a natural host of the pathogen, often asymptomatic or subclinical
infection
disease reservoir
this is a group of viruses transmitted by mosquitos, ticks, or other arthropods
arbovirus
what is the vector of West Nile virus
culex mosquito
what is the vector of the dengue virus
Aedes mosquito
what is the vector of yellow fever
Aedes mosquito
what is the vector of malaria
Anopheles mosquito
what is the vector of chikungunya
Aedes mosquito
what is the vector of leishmaniasis
sandflies
what is the vector of lyme disease
, Ixodes spp. ticks
what is the vector of hantavirus
rodents
what are mosquito prevention strategies
repellant, protective clothing/netting, avoid peak biting hours, keep mosquitos
from laying eggs nearby
ebola virus is part of filoviridae and is a filamentous, ______ (enveloped or non
enveloped) _________ (RNA or DNA) virus
enveloped, negative strand RNA virus
what does ebola virus produce
glycoprotein - inhibit neutrophil activation/antibody actions
proteins - block interferon production/action
where does ebola virus replicate
endothelial cells, monocytes, macrophages
what can ebola virus cause in immune system
cytokine storm - extensive tissue necrosis - vascular injury/leakage
T/F: ebola virus is extremely contagious
true
what is the clinical syndrome of ebola virus
flu like illness progresses to HA/myalgia..N/V/D in days, rash
possible...hemorrhage from multiple sites
what is the % of ebola virus mortality
40-90%
how is ebola virus diagnosed
antigen/RNA is suspected; limited to CDC or specialized lab
what level isolation procedures for ebola virus
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