ASU BIO 340 Exam 3 Questions With
Complete Solutions
What cwill cbe cthe ceffect con ctranscription cwhen can cinhibitor cis cin cplay?
A. cAllow ctranscription cB. cPrevent ctranscription c- ccorrect canswers✔✔B cExplanation:
cAn cinhibitor cprevents cactivator cfrom cbinding cto cDNA; cactivators care cused cin
cpositive cregulation c(increasing ctranscription) c- cthus, cthe cinhibitor cprevents cthe
cactivator cfrom cpositive cregulating c(increasing) ctranscription.
What cwill cbe cthe ceffect con ctranscription cwhen can cinducer cis cin cplay? c
A. cAllow ctranscription cB. cPrevent ctranscription c- ccorrect canswers✔✔A cExplanation:
cWhen can cinducer cis cin cplay, cit cwill callow ctranscription.
For ca cgene cunder cpositive ccontrol, cwhich cof cthe cfollowing cwould cprevent
ctranscription? c
A. cRepressor cB. cCorepressor cC. cInducer cD. cEffector cE. cInhibitor c- ccorrect
canswers✔✔E cExplanation: cPositive cregulation cincludes cactivators c(affected cby
ceffectors cand cinhibitors); cinhibitors cprevent cactivator cfrom cbinding cto cDNA, cthus
cpreventing ctranscription.
For ca cgene cunder cnegative ccontrol, cwhich cof cthe cfollowing cwould cyou cexpect cto
cfind cbound cto cthe crepressor cif cthere cis cactive ctranscription? cA. cRepressor cB.
cCorepressor cC. cInducer cD. cEffector cE. cInhibitor c- ccorrect canswers✔✔C
cExplanation: cIn cnegative cregulation, cthere care crepressors c(affected cby
ccorrepressors cand cinducers). cIf cthere cwere ca ccorepressor, cthe crepressor cwould
csuccessfully cbind cto cthe coperator cand cprevent ctranscription. cInducers, chowever,
cprevent cthe cbinding cof cthe crepressor c- cthus ccausing ca cprevention cof cit cdoing cits
cjob, cand callowing ctranscription.
Which cmolecule cserves cas cthe cinducer cfor cthe clac coperon? c
A. ccAMP cB. cGlucose cC. cLactose cD. cAllolactose c- ccorrect canswers✔✔D
cExplanation: cAllolactose cis cthe cmolecule cthat cbinds cto crepressor cprotein, cmaking cit
cunable cto cbind cto cthe coperator.
Which cof cthe cfollowing cconditions cwill cresult cin cthe cgreatest clevels cof ctranscription
cof cthe clac coperon? c
A. cLactose cabsent, cglucose cabsent cB. cLactose cabsent, cglucose cpresent cC. cLactose
cpresent, cglucose cpresent cD. cLactose cpresent, cglucose cabsen c- ccorrect
canswers✔✔D cExplanation: cFrom cthe cperspective cof cthe ccell, cit cis cmost cefficient cto
crepress cexpression cof cthe cgenes callowing cfor cmetabolism cof clactose cwhen cit's
cabsent, cto callow cit cwhen cpresent, cbut conly cto cprioritize cit cwhen cglucose c(the
cpreferred cfood csource) cis cabsent. cIn cC, callolactose cwill calso cbe cpresent, callowing
, ctranscription, cbut cpositive cregulation c(i.e. cincrease cin ctranscription) conly chappens
cas cin cD, cwhen cglucose cis cabsent.
Which cof cthe cfollowing cmutations cwill cresult cin cthe clowest clevel cof ctranscription cof
cthe clac coperon cwhen clactose cis cpresent? c
A. cAn coperator cmutation cthat cprevents cbinding cof cthe clac crepressor cB. cA cmutation
cin cthe clac crepressor cthat cprevents cit cfrom cbinding cto cthe coperator cC. cA cmutation
cin cCAP cthat cprevents cit cfrom cbinding cto cthe cCAP cbinding csite cD. cA cmutation cin
cthe clac crepressor cthat cprevents cit cfrom cbinding callolactose c- ccorrect canswers✔✔D
cExplanation: cA c- cif crepressor ccan't cbind, cthe cgene cwill cbe cpermanently cturned con,
cthere cwill cbe ctranscription. cB c- cexactly cthe csame ceffect cas cA. cC c- c"tempting cbut
cwrong"; cCAP ccan't cbind, cwill ccause clower cbut cnot ctotal cprevention cof ctranscription.
cD c- ccorrect canswer; cif cthe cinducer cis ctotally cineffective, cthen cthe crepressor cwill
cpermanently cbind cto coperator cand ctotally cprevent ctranscription.
The cregulatory celements cin cthe clac coperon cact cto: c
A. cRepress ctranscription cwhen cthere cis cno clactose cpresent cB. cRepress ctranscription
cwhen cthere cis clactose cpresent cC. cActivate ctranscription cwhen cthere cis cno cglucose
cpresent cD. cActivate ctranscription cwhen cthere cis cglucose cpresent cE. cA cand cC c-
ccorrect canswers✔✔E cExplanation: cThe ccell cwants cto cboth crepress ctranscription
cwhen cthere cis cno clactose cpresent cand cactivate cit cwhen cglucose cis cabsent c(C
c"slightly cless cgood" canswer cthan cA, cbut cstill ctrue). cSimilar cto cClicker cQuestion c6
A cbacterium cneeds cto cmake ca ccertain clipid cthat cit ccannot cobtain cfrom cits
cenvironment. cThat csame clipid cis cinvolved cin cregulating cthe cexpression cof cthe
cenzymes cthat cmake cit. cWhich cof cthe cfollowing cis cthe cmost clikely cregulatory
cfunction cof cthe clipid?
cA. cEffector cB. cActivator cC. cInducer cD. cCo-repressor cE. cOperator c- ccorrect
canswers✔✔D cExplanation: cIf cyou chave cthat clipid, cyou cwould cwant cit cto cnot cmake
cany cmore. cSo, cif cyou chave cthe clipid cin cthe ccell, cyou cwould cwant cto cturn coff cthe
ctranscription, cso cit cwould clikely cbe cinvolved cin cnegative cregulation. cEffectors cand
cactivators care cboth cinvolved cin cpositive cregulation. cAn cinducer cis cunder cnegative
cregulation cbut cits cjob cis cto cturn con ctranscription. cA cco-repressor cwill conly cturn cthe
cgene coff cif cthere cis ca csignal cthe ccell ccan csense. cOperator cis ca cpiece cof cDNA.
A cbacterium cis cunable cto ctransport clactose cinto cthe ccell cto cbe cbroken cdown. cWhich
cgene cis clikely cmutated cin cthis cbacterium? c
A. clacZ cB. clacY cC. clacI cD. clacP cE. clacO c- ccorrect canswers✔✔B cExplanation: cIf
cyou ccan't ctransport clactose, cthen cit cmeans cpermease cisn't cworking. cSo clacY cis
clikely cmutated csince cthat cis cthe cgene cthat cencodes cpermease.
Under cwhich cconditions cwill cE. ccoli cmake cthe cleast camount cof cbeta-galactosidase? c
A. cI+ cO+ cZ+, cglucose cabsent, clactose cpresent cB. cIs cOc cZ+, cglucose cpresent,
clactose cabsent cC. cI- cO+ cZ+, cglucose cabsent, clactose cabsent cD. cIs cO+ cZ+,
cglucose cabsent, clactose cpresent c- ccorrect canswers✔✔D cExplanation: cA cis cwild
ctype, cso cthe cexpression clevel cwould cbe chigh, cB chas ca csuper crepressor, cmeaning