Nagelhout Pharmacology Exam 1 Review Questions And Answers Graded A+ 2024.
Pharmacology - correct answer. the study of the effect of chemicals on living tissue
Pharmacokinetics - correct answer. the study of the absorption, distribution, metabolism and excretion of drugs
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Pharmacology - correct answer. the study of the effect of chemicals on living tissue
Pharmacokinetics - correct answer. the study of the absorption, distribution,
metabolism and excretion of drugs
Pharmaceutics - correct answer. the formulation and preparation of drugs
pharmacoeconomics - correct answer. the study of the economic impact of drugs
toxicology - correct answer. the study of the harmful effects of chemicals
pharmacognosy - correct answer. the study of the medicinal uses of naturally
occurring compounds
pharmacy - correct answer. the preparation and dispensing of drugs
pharmacogenetics - correct answer. genetic influences by and on drugs
pharmacodynamics - correct answer. physiological and biochemical mechanism of
action of drugs
(e.g. receptor theory)
pharmacogenomics - correct answer. identifies discrete genetic differences among
individuals that play a critical role in drug response
pharmacoepidemiology - correct answer. is the study of the use and effects of drugs
on large groups of people
ED50 - correct answer. Effective dose in 50% of the population
TD50 - correct answer. Toxic Dose in 50% of the population
, LD50 - correct answer. Lethal Dose in 50% of the population
Therapeutic index - correct answer. LD50/ED50
Therapeutic window - correct answer. TD50/ED50
Two types of ligands - correct answer. Agonist or Antagonist
Reversible binding of ligands is called - correct answer. competitive
non-reversible binding of ligands is called - correct answer. noncompetitive
5 types of chemical bonds in order of increasing strength - correct answer. van der
waals, hydrophobic, hydrogen, ionic, covalent
5 types of chemical bonds in order of decreasing strength - correct answer.
covalent, ionic, hydrogen, hydrophobic, van der waals
Occupation of receptors by ligands is governed by: - correct answer. affinity
Activation of receptors by ligands is governed by: - correct answer. efficacy
A dose response curve can show: - correct answer. Affinity (potency), Efficacy,
Variability, Slope
Up regulation - correct answer. an increase in receptor proteins as a response to
chronic blockade
Down regulation - correct answer. Desensitization (refractoriness) following
continued stimulation (agonists). Chronic beta stimulant use for asthma resulting in
increased dose necessary is an example
Drug Interaction - correct answer. Alteration in the therapeutic action of a drug by
concurrent administration of other exogenous chemicals
1+1 = 2 - correct answer. Addition; The combined effect of two drugs acting via the
same mechanism is equal to that expected by simple addition of their individual actions
Ex) midazolam + diazepam
1+1=3 - correct answer. synergism; The combined effect of two drugs is greater
than the sum of their individuals effects
Ex) Midazolam + Propofol
1+0=3 - correct answer. potentiation; The enhancement of the action of one drug by
a second that has no detectable action of its own.
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