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Lupus Nursing School Notes

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The MUST KNOW points concerning “Lupus”, for nursing school. Get all the must know material condensed down for nursing exams and NCLEX!

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  • November 5, 2024
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  • 2024/2025
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courtneywood1
Hus

· ⑧ · O
· . ⑧
o

O
O
· O
O O ·
·



* SLE
multisystem inflamm autoimmune disease
:
.




affects skin joints pleura pericardium renal hematologic
-




, , , , ,
neuro
*
unpredictable course (alt remission / exacerbation) .




-

Black. Asian . Hispanic ,
Native Am .,
Pacific Islander =
↑ risk
>
women = risk lage15-45)

Patho poss genetics (HLA-DR2/DR3)
=
:
- unknown ;
-hormones ( worse wh menses oral contracept during/after , , pregt
*Worse in
postpartum
Epstein Barr hyperact.
-



=
Stim immune .




Environmental (sun/UV/chemicals toxins silica dust)
-


-


,




Drugs (sulfa diuretics tetracycline)
-




, ,


*
After months -




urs
*
Body makes various antibodies against nucleic acid , erythro coag proteins lymphocytes plts
., , ,



*
Autoimmune reactions againstCell nucleus (DNA)
-




* Inflamm = tissue destruction
↳ overaggressive autoimmune response (B/c B$T cells)
* SLE Type Ill hypersens response
=
.




· Manifestations * varies from mild-rapid progressive (no same pattern
Common tissue involved Skin/muscle liking of lungs heart nervous tissue Kidneys
-
:
, , ,
,




Askin-fever-weight loss joint pain fatigue Pneumonia
-
-




Grow back
rash can

alopecial Butterflyrash-discoid/palmar erythema mucosal ukers -proteinuria
-
-
-




Often 1st
Glomerulonephritis
-Endo/MyolPeri-carditis-PE-Rayhands Phenomenon hematuria
-
-




Symp .




arthritis stroke-Seizures Periph Neuropathy psychosis anemia
- - -
-

.




cause deform I .




/Swan neck sublux) Splenomegaly Thrombocytopenia Abd pain/diarrhea/NI--menstrual abhorm
-
- -



.



,




skin lesions (sun exposed areas photosensativity
-

-




chronic cut Lupus discoid lesion scalp face
· : -

.




bacute cut lupus red-ring shaped lesion
· .
:
> not thick/scaly
cute lupus lesion when "active"
· Butterfly rash ("Malar Rash"
: =




-tachypnea-cough pleurisy-dysrythmia Secondary antiphospholipid Synd (APS)
- -

.




I
&




End Stage Venal disease (ESRD) leukopenia ↳ coag. disorder 14 risk stroke gangrene,
- -



,



heart attack)
* Resistant to Blood thinning from Aspirin


· TX for Lupus Kidney Probs
1) corticosteroids Immunosuppr.
lazathioprine ; cyclosporine ; Oral Prednisone ; IV Methylprednisolone
2) Monoclonal Antibody
/belimumab-Benlystal
'voclosporin-Lupkynis) -




Stop T cell




*
Hydroxychloroquine ↓ risk for clots
:




BIC Asprin wont

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