MS1 exam 1 study guide Questions
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Priority assessment for wound infection
✓ Purulent drainage, odor, redness; temperature; Assess for location, size, depth, color
and drainage
Promotion of wound healing
✓ Requirements include adequate nutrition, strong immune system, a diet high in
protein, carbohydrates, vitamins and moderate fat, high fluid intake and platelets are
also important to promote wound healing
What is the vascular response
✓ Local arterials briefly undergo vasoconstriction; then the vessels dilate; chemical
mediators facilitate fluid movement; both vasodilation and increased capillary
permeability causes redness, heat and swelling at the site of injury
What is the cellular response
✓ Neutrophils and monocytes move from circulation to the site of injury; chemotaxis;
neutrophils arrive within 6 to 12 hours and die within 12 to 48 hours, accumulate &
make pus; monocytes arrive within 3 to 7 days, can live in the tissues for months &
turn into macrophages
Phases of the inflammatory response
✓ Vascular response, cellular response, formation of exudate and healing
Priority assessment related to immunosuppression
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✓ Healing takes place when wound margins are neatly approximate it, as in a surgical
incision or a Papercut; includes three phases
Initial or inflammatory phase of primary intention
✓ edges of the incision are aligned & sutured in place; area fills with blood from cut
vessels; clot forms & platelets release growth factors to begin healing; area is
composed of fibrin clots, erythrocytes, neutrophils & other debris; macrophages
ingest cellular debris
Granulation phase of primary intention
✓ Tissue includes proliferating fibroblasts & capillary sprouts,WBCs, exudate & loose,
semifluid ground substance; wound is pink & vascular, red granules are present;
wound is friable at risk for dehiscence & resistant to infection; surface epithelium at
the wound edges begins to regenerate
Maturation phase and scar contraction of primary intention
✓ Begin seven days after injury; collagen fibers are further organized in the remodeling
process occurs; fibroblasts disappear; contraction of the healing area helps to close
the defect and bring the skin edges closer together; a mature scar is then formed
Secondary intention
✓ Large amounts of exudate and wide, a regular wound margins with extensive tissue
loss; edges cannot be approximated; may need to be debrided before healing can
take place; the major differences between secondary and primary are the greater
defects and the gaping wound edges
Tertiary intention
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