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CSB520 exam questions with complete solutions 2024
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CSB520 exam questions with complete solutions 2024
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CSB520 exam questions with completesolutions 2024
What jis japoptosis? j- jANS✓✓-- jProcess jof jprogrammed jcell jdeath jthat jis jnot
jreversible
-Active jprocess jthat jrequires jenergy
-Can jbe jpathological jor jphysiological
-Can joccur jin jsingle jcells
What jis jnecrosis? j- jANS✓✓--Sudden jcell jdeath jthat jis jnot jreversible
-Passive jprocess jthat jdoes jnot jrequire jenergy
-Pathological
-Impossible jfor ja jsingle jcell jto jdie jvia jnecrosis jas jit jalso jkills jneighbouring
jcells
-Stimulates jinflammation
What jdoes jthe jtype jof jcell jdeath jdepend jon? j- jANS✓✓-Depends jon jthe
jseverity jand jduration jof jthe jstressor jand jhow jhealth jthe jcell jwas jto jbegin jwith
What jis jan jinfarct? j- jANS✓✓-An jarea jof jnecrotic jtissue jthat joccurs jthrough
jirreversible jinjury jusually jsudden jin jnature
What jdetermines jwhether ja jstimulus jcauses jatrophy jor jinfarction? j- jANS✓✓-1.
jCell/Tissue jType
2. jCell jhistory
3. jStimuli
4. jSeverity jand jduration
What jeffect jdoes jageing jhave jon jcells jand jorgans j- jANS✓✓-- jAutophagy jability
jdeclines jwith jage
-Defective jremoval jof jdamaged jmitochondria jresults jin jincreased jfree jradical
jgeneration
-Therefore jincreased jstressors joften jresult jin japoptosis jor jnecrosis jof jthe jcell
What jis jhyperplasia? j- jANS✓✓-Increase jin jcell jnumber jif jtissue jis jlabile jor
jstable
What jis jhypertrophy? j- jANS✓✓-Increase jin jcell jsize
,What jcellular jadaptations jlead jto jan jincrease jin jthe joverall jsize jof jan jorgan? j-
jANS✓✓-Hyperplasia jand jHypertrophy
What jform jof jcell jdeath joccurs jduring jnormal jembryogenesis? j- jANS✓✓-
Apoptosis
What jis jmetaplasia? j- jANS✓✓-The jchange jfrom jone jnormal jadult jor jwell
jdifferentiated jcell jtype jinto janother jnormal jadult jor jwell-differentiated jcell jtype
How jdoes jnecrosis jcause jinflammation? j- jANS✓✓-During jnecrosis jthe jcell
jlyses jso jthe jcontents jof jthe jcell jspill jout jkilling jsurrounding jcells j&
jstimulating jan jinflammatory jresponse.
Does jmetaplasia jalter jthe jfunction(s) jof jthe jcells j& jis jmetaplasia jreversible? j-
jANS✓✓-Yes jstructure j& jfunction jare jlinked jso jwhen jthe jstructure jor jcell jtype
jchanges jso jdoes jthe jcells jcapabilities. jMetaplasia jis ja jreversible jadaptation.
What jis jautophagy? j- jANS✓✓-Cell jshrinkage jthrough jself-eating
What jis jatrophy? j- jANS✓✓-decrease jin jcell jsize
How jdoes jatrophy jdiffer jbetween jyoung jand jelderly jtissues? j- jANS✓✓-In
jyoung jhealthy jtissues jthat jare jsubjected jto jstress, jcells jwill joften jchoose jto
jshrink jthrough jautophagy jwhereas jas jwe jage jthe jability jfor jour jcells jto
jundergo jautophagy jdeclines jmeaning jthat jcells jare jmore jlikely jto jundergo
japoptosis
What jare jthree jtypes jof jcells? jWith jexamples jof jeach jcell jtype j- jANS✓✓-(1)
jliable j(dividing) j- jepithelial jcells jof jskin, jGIT, jreproductive, jurinary jand jbladder
jor jhaemopoietic jstem jcells
(2) jstable j- jepithelial jcells jof jlung, jliver, jkidney jand jpancreas jor jsmooth jmuscle
jcells, jfibroblasts jand jendothelial jcells
(3) jpermanent j(non-dividing) j- jcardiac jmyocytes, jskeletal jmyocytes jand jglial
jcells jof jneurons
What jis jinvolution? j- jANS✓✓-The jprocess jby jwhich jthe juterus jreturns jto jits
jpre jpregnant jstate jdue jto jdecreased jlevels jof jhormones jfollowing
jbirth/abortion
What jis jneoplasia? j- jANS✓✓-New jabnormal jtissue jgrowth
What jis ja jtumour? j- jANS✓✓-Swelling jcaused jby jabnormal jtissue jgrowth-
jdoesn't jmatter jwhether jit's jbenign jor jmalignant
What jis ja jmalignant jtumor? j- jANS✓✓-a jmass jof jcancer jcells
, What jis jdysplasia? j- jANS✓✓-An jabnormal jprecancerous jchange jthat jis jnot jan
jadaption
What jdoes jin jsitu jmean? j- jANS✓✓-Confined jabove jthe jbasement jmembrane,
jhasn't jpenetrated jbasal jlayer jyet
What jis jmeant jby jmetastasis? j- jANS✓✓-Some jof jthe jcells jfrom jthe jprimary
jtumour jhave jtravelled jto jdistant jsites
What jis jthe jbasic jrisk jfactor jfor jthe jdevelopment jof jmutation jand
jtumourgenesis? j- jANS✓✓-Proliferation. jA jhigher jincidence jof jdivision
jincreases jrisk jof jdeveloping jcancer
What jare jthe jeight jbehavioural jchanges jthat joccur jin jcancer jcells j? j- jANS✓✓-
(1) jself-sufficiency jin jgrowth jsignals j(proliferation jwithout jexternal jstimuli)
(2) jinsensitivity jto jgrowth-inhibitory jsignals
(3) jevasion jof japoptosis
(4) jlimitless jreplicative jpotential
(5) jsustained jangiogenesis
(6) jability jto jinvade jand jmetastasise
(7) jdefects jin jDNA jrepair
(8) jpredilection jfor jglycolysis jeven jwith/without jpresence jof joxygen j(Warburg
jeffect)
What jtwo jcellular jadaptations jincrease jthe jrisk jof jtumour jdevelopment? j-
jANS✓✓-Metaplasia j& jhyperplasia
What jare jthe j3 jways jwhich jcancer jcan jspread? j- jANS✓✓-Through jblood,
jlymph jand jdirect jseeding
What jtwo jreasons jare jcarcinomas jthe jmost jcommon jtype jof jcancer? j- jANS✓✓-
Epithelial jcells jare jstable jor jlabile jso jeither jconstantly jdividing jor jable jto jdo jso
jwhen jstimulated. jEpithelial jcells jare jon jthe jfront-line, jbetween jour jinner jbodies
j& jpotentially jdamaging jstimuli.
What jare jthe jdifferences jbetween jbenign jand jmalignant jtumours? j- jANS✓✓-
Benign
- jdo jnot jmetastasise- jencapsulated
- jhomogenous j(uniformity jof jcells)
j- jone jmutation
-well-differentiated
- jslower jgrowing
Malignant
- jcan jmetastasise- jheterogenous j(lacks juniformity jof jcells) j
- jmultiple jmutations- jwell-differentiated jor jundifferentiated
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