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NRNP 6675 FINAL EXAM LAST EXAM TEST 2024/2025 GRADED A+ COMPLETE QUESTIONS AND VERIFIED ANSWERS
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NRNP 6675 FINAL EXAM LAST EXAM TEST 2024/2025 GRADED A+ COMPLETE QUESTIONS AND VERIFIED ANSWERS
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NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)Study online at https://quizlet.com/_d3fvek
1. The 1/2 life of lithium is about? 24 hours
2. Fluoxetine is the SSRI with the ______ WD lowest due to long half life
risk?
3. What antipsychotics are good for pts who Antipsychotics with long
miss doses of their meds? half-lives:
1. Cariprazine(Vrylar): (2-4
days-active metabolites up
to 3 weeks)
2. Abilify (3 days)
3. Brexipiprazole (4 days)
4. Pimozide (4-5 days)
5. Pimavanserin (2 days, ac-
tive metabolites 8 days)
4. Disulfiram's alcohol interactions persist for LONG Half life--2-3 days
up to how long after the medication is
stopped? persist up to 2 weeks follow-
ing stopping
5. What is the only TCA with a long half life? Protriptyline (Vivactil)
6. Most psychotropics have a medium range 24 hours
1/2 life of approx?
7. what does "steady state" mean in relation to steady state means that you
1/2 life? are eliminating the drug at
the same overall rate that
you are ingesting it
8. Lithium reaches its 'steady state' when? 5 half lives
example:
Day 1: Start pt on Lithium
600 mg daily
Day 2: (24 hours later) the
amount left in his body is
300 mg (day 2 min) because
24 hours has passed--one
, NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)
Study online at https://quizlet.com/_d3fvek
1/2 life--therefore the pt has
excreted 1/2 of the initial
amount.
THEN the pt takes his 2nd
dose of 600 mg on DAY 2-re-
sulting in a max dose of 900
(300 mg left in body + 600
mg of 2nd dose).
DAY 3: starts off with 450 mg
(1/2 of the 900 mg in pt's sys-
tem) and after taking the day
3 600 mg dose, the pt now
has a total of 1050 mg.
9. Due to the steady state of Lithium, when do 5 half lives
we draw a blood level?
if you check any earlier, the
trough level will underesti-
mate the actual level the pt
is on after achieving steady
state
10. Fluoxetine has a half life of about? 2 weeks 1/2 life
take 2.5 months to achieve
steady state
11. Most psychotropic medications operate in "when you double the dose,
this fashion: the serum dose doubles."
*minus three SRIs and
three anticonvulsants (Flu-
oxetine, fluvoxamine, paxil,
gabapentin, valproate and
carbamazepine)
12. _________induces it's own metabolism, A. Carbamazepine (Tegre-
hastening excretion and shortening it's half tol)
life
*this effect begins to "rev
, NRNP 6675 FINAL EXAM LAST EXAM EVERRRRR (minus boards)
Study online at https://quizlet.com/_d3fvek
up" after 2-4 weeks--which
is why a carbamazepine lev-
el is so important on obtain-
ing 1-2 months after starting
Tegretol.
13. Carbamazepine (Tegretol) level should be 1-2 months due to Tegre-
checked how soon after starting to take this tol inducing it's own metab-
med? olism, hastening excretion
and shortening it's half life.
14. _____ has trouble getting a "serum" level A. Valproate Acid (De-
because it binds to proteins that render it pakote)
therapeutically inactive?
-this is particularly true at
the lower levels (eg. <50
mcg/mL), so you can ex-
pect dose changes to make
a more dramatic difference
when the pt's depakote level
is in the higher range
15. _______'s serum level is the opposite of Val- Gabapentin
proic Acid: it rises quickly at first and then
slows down? *gabapentin saturates the
transporters that absorb it in
the small intestine, causing
its levels to rise at a snails
pace when the dosage goes
above a certain saturation
point (around 900 mg/day).
-from there, the sat-
uration trickles down;
@ 900 mg/day--60%
is absorbed. @ 1200
mg/day--50 % is absorbed.
@3000 mg/day--30% of the
gabapentin is absorbed.
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