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NURS 8024 PHARM TEST 3 PT. 1 QUESTIONS AND ANSWERS 2024 $12.99   Add to cart

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NURS 8024 PHARM TEST 3 PT. 1 QUESTIONS AND ANSWERS 2024

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NURS 8024 PHARM TEST 3 PT. 1 QUESTIONS AND ANSWERS 2024

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  • November 7, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURS 8024 PHARM
  • NURS 8024 PHARM
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NURS 8024 PHARM TEST 3 PT. 1

Aminioglycosides - ANSWERS-Gentamicin, tobramycin, amikacin, streptomycin



Aminoglycosides MOA - ANSWERS-inhibit bacterial protein synthesis

-bactericidal

-concentration dependent killing

-killing continues after plasma levels decline; single large dose rather than
multiple small doses



Aminoglycosides indications - ANSWERS--Used to kill gram-negative bacteria, such
as Pseudomonas spp., Escherichia coli, Proteus spp., Klebsiella spp., Serratia spp.

-Often used in combination with other antibiotics for synergistic effects (beta-
lactams or vancomycin)

-Used for certain gram-positive infections that are resistant to other antibiotics

-Inhaled tobramycin in cystic fibrosis



Tetracycline - ANSWERS--inhibit bacterial protein synthesis

-broad spectrum, bacteriostatic

-doxycycline & minocycline NOT excreted renal-ly



Tetracycline Pharmacokinetics - ANSWERS--time dependent killing

, -absorption IMPAIRED by FOOD, DAIRY, CALCIUM ANTACIDS



ADE of tetracyclines - ANSWERS--photosensitivity

-bacterial superinfections

-deposition in developing bones and teeth

-contraindicated in below 8 yrs old and pregnancy



Tetracycline indications - ANSWERS--used in CAP (alt to macrolides)

-Syphillis (alt use)

-H. Pylori

-Lyme disease

-Malaria prevention/prophylaxis

-low dose acne trmt



Tigecycline (Tygacil) - ANSWERS-Glycylcycline

-v broad spectrum

-IV only

-time dependent killing

-bacteriostatic

MOA: protein synthesis inhibitor



Macrolides: dist, elim, & resis - ANSWERS--No CSF penetration

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