HEMATOLOGY CASE STUDIES MODULE 1
QUESTIONS AND ANSWERS 2024 - 2025
Which,of,the,following,is,responsible,for,the,most,serious,laboratory,errors?,,ANS,-
,,Misidentifying,the,patient
Indicate,the,correct,order,that,blood,should,be,drawn,,ANS,-,,1,blood,culture,bottles
2,tubes,containing,no,anticoagulant
3,coagulation,tubes
4,EDTA,tubes
Forcing,blood,drawn,in,a,syringe,into,a,lavender,tube,could,result,in:,,ANS,-,,hemolysis
Of,the,following,tubes,,which,color,is,acceptable,for,testing,if,the,blood,is,clotted?,,ANS,-,,Red
Will,an,individual,living,at,high,altitudes,have,a,higher,or,lower,hematocrit,than,one,living,at,sea,level,(A)?,
Why,(B)?,,ANS,-,,A.,higher
B.,Lower,oxygen,tension,at,high,altitude,will,stimulate,kidneys,to,excrete,more,erythropoieten,to,increase
,RBC,production.
Where,on,a,manual,smear,will,larger,cells,such,as,blasts,be,found?,,ANS,-
,,Near,the,edges,or,at,the,feathered,edge
Describe,(A),the,cause,of,water,artifact,on,a,stained,blood,smear,,(B),what,it,resembles,on,the,blood,smea
r,,and,(C),how,to,prevent,the,formation.,,ANS,-
,,A.,artifact,caused,by,inadequate,drying,of,smears,before,staining
B.,makes,cells,look,hypochromic
C.,allow,cells,to,dry,longer,or,fix,in,methanol
Which,condition,is,most,likely,on,a,patient,with,a,WBC,of,25,000/uL,,platelet,count,of,11,000/uL,,and,a,lef
t,shift,including,several,blasts?,,ANS,-,,acute,lukemia
,If,a,PTT,was,performed,on,serum,instead,of,plasma,,the,result,would,be:,,ANS,-,,higher,than,plasma
Which,of,the,following,is,an,acceptable,site,for,blood,collection?,,ANS,-
,,below,a,cast,(NOT,same,side,as,a,recent,mastectomy,,above,an,IV,or,thrombosed,vein)
A,specimen,from,a,difficult,draw,has,flags,for,decreased,RBC,count,,decreased,hematocrit,,and,increased,
hemoglobin.,What,should,be,suspected,(A)?,What,is,the,best,remedy?,,ANS,-,,A.,hemolyzed,specimen
B.,request,a,new,sample
An,automated,cell,counter,prints,a,WBC,of,220,000/uL.,What,other,parameters,will,be,affected,(A)?,How,
can,the,affected,parameter(s),be,corrected?,,ANS,-,,A.,Hgb,,Hct,and,RBC,count
B.,dilute,WBC,and,recount;,subtract,WBC,from,RBC;,calculate,indices;,perform,manual,hematocrit;,use,hg
b,value,from,dilution,and,multiply,by,dilution,factor,or,perform,manual,hgb,after,removing,WBCs,through,
centrifuge
A,cell,counter,prints,a,platelet,count,of,36,x,10^3/uL.,The,manual,smear,has,platelet,clumps.,What,should,
be,done?,,ANS,-,,Vortex,and,repeat,or,redraw,using,sodium,citrate,or,by,fingerstick
What,is,the,most,common,reason,for,platelet,clumps?,,ANS,-
,,inadequate,or,delayed,mixing,of,the,collection,tube,after,phlebotomy;,fingerstick,samples,are,also,prone
,to,platelet,clumps
Why,is,it,important,to,centrifuge,coagulation,tests,for,the,time,and,speed,listed,in,the,procedure?,,ANS,-
,,platelets,must,be,removed,from,the,plasma,and,they,are,the,last,to,spin,out,(platelets,activate,the,coagu
lation,cascade)
When,preparing,a,cytospin,smear,,which,of,the,following,preserves,the,cells,and,keeps,them,intact,as,the
y,are,deposited,onto,the,slide?,,ANS,-,,albumin
Reference,Ranges,,ANS,-,,WBC:,4,000,-,11,000/uL
Plt:,150,000,-,450,000/uL
Hgb:,Adult,Male:,14.0,-,18.0,g/dL
, Adult,Female:,12.0,-,15.0,g/dL
Infant:,16.0,-,22.0,g/dL
Toddler:,9.5,-,15.0,g/dL
MCV:,Adult:,80,-,100,fL
Infant:,95,-,125,fL
Severe,lipemia,interferes,with,all,of,the,following,EXCEPT:,,ANS,-,,Hct,(interferes,with,Hgb,,MCH,and,PTT)
How,can,hematology,results,be,corrected,when,lipemia,is,present?,,ANS,-
,,For,CBC:,saline,replacement,is,most,commonly,used
For,Coag:,remove,lipemia,by,using,an,ultra,centrifuge,or,run,tests,on,fibrometer,or,other,mechanical,met
hod,not,affected,by,lipemia
Describe,the,appearance,of,a,blood,smear,made,from,a,2,day,old,lavender,top.,,ANS,-,,RBC:,crenated,cells
WBC:,vacuolated,or,can,disintigrate
Plt:,can,clump,or,disintigrate
Hct:,RBCs,swell,increasing,MCV,and,automated,Hct
Accept,,reject,or,clarify:,green,top,for,coagulation,,ANS,-,,reject;,recollect,in,blue,top
Accept,,reject,or,clarify:,PTT,on,a,blue,top,that,was,collected,2,days,ago,for,a,PT,,ANS,-
,,reject:,PTTs,need,fresh,plasma
Accept,,reject,or,clarify:,patient,has,Hct,of,60%,and,elevated,PTT,,ANS,-
,,reject;,recollect,with,adjusted,anticoagulant
Accept,,reject,or,clarify:,lavender,top,on,an,inpatient,with,no,name,,ANS,-
,,reject;,redraw,and,properly,label
Accept,,reject,or,clarify:,PTT,drawn,from,an,indwelling,line,with,no,blood,discarded,prior,to,filling,blue,top,
,ANS,-,,reject;,draw,from,vein