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Exam (elaborations)

NU301 Pharmacology FINAL Exam And Answers(Revised & Updated).

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Pharmacodynamics - Answer The process by which a medication works on the body. Pharmacokinetics - Answer The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. Half-life - Answer Time it takes for a drug to decrease in amount by half Chemi...

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  • November 11, 2024
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NU301 Pharmacology FINAL Exam And
Answers(Revised & Updated).
Pharmacodynamics - Answer The process by which a medication works on the body.



Pharmacokinetics - Answer The process by which drugs are absorbed, distributed within the body,
metabolized, and excreted.



Half-life - Answer Time it takes for a drug to decrease in amount by half



Chemical name of drugs - Answer the name of the medication that reflects its chemical composition
and molecular structure (ex. isobutylphenylpropanoic acid)



Generic name (nonproprietary name) - Answer Name given to a medication by the United States
Adopted Names Council (ex. ibuprofen)



Trade name - Answer Proprietary name of a drug assigned by the manufacturer; also called the brand
name or product name.



Rights of Safe Medication Administration - Answer Right client/patient

Right medication/drug

Right dose

Right time

Right route

Right documentation

Right client education

Right to refuse

Right assessment

Right evaluation

,Types of Analgesic Agents - Answer Opioids

Narcotic Antagonists

Antipyretic

NSAIDs

etc.



Opioid Prototype - Answer morphine



Action of Morphine - Answer Binds to opioid receptors (Mu & Kappa) in the brain and spinal cord



Indications for Morphine - Answer prevent/ relieve severe acute or chronic pain; before, during and
after surgery; before and during diagnostic procedures; labor & delivery



Adverse Effects of Morphine - Answer Respiratory depression

Orthostatic hypotension

Excessive Sedation

Constipation/ Urinary Retention

Cough suppression

Biliary colic



Nursing Implications of Morphine - Answer watch for s/sx of toxicity: Severe respiratory depression;
coma; pinpoint pupils



General principles of Morphine - Answer Metabolized: liver; Excreted: urine, bile; T1/2: 1.5-2 hours

Routes:PO, IV, IM, SUBQ, Intrathecal, epidural



MORPHINE IS THE FIRST CHOICE FOR SEVERE PAIN



No ceiling

,Regular schedule



Narcotic Antagonist Prototype - Answer Naloxone (Narcan)



Action of Naloxone (Narcan) - Answer Block effects of opioids



Indications of Naloxone (Narcan) - Answer Reversal of signs or opioid excess



Adverse Effects of Naloxone (Narcan) - Answer Dysrhythmias

HTN

Hypotension

N/V



Nursing Implications for Naloxone (Narcan) - Answer Likely to need repeated injections



Titrate with care to avoid acute withdrawal



General Principles of Naloxone (Narcan) - Answer Onset: within minutes of parenteral administration
(almost immediately if IV)



T1/2: 30 to 81 minutes



Metabolized in liver



Excreted by kidney



Prostaglandin inhibitors - Answer NSAIDs. Medications that act on prostaglandins, compounds that
regulate muscle contractions (& Acetaminophen)

, Antipyretic Prototype - Answer Acetaminophen (Tylenol)



Action of Acetaminophen (Tylenol) - Answer Inhibits prostaglandin synthesis in central nervous system



Indications of Acetaminophen - Answer Relief of mild pain or fever, headache, muscle aches



Adverse Effects of Acetaminophen - Answer HEPATOXICITY



Nursing Implications of Acetaminophen - Answer Treatment of poisoning"

Acetylcysteine



NSAID Prototype(s) - Answer Ibuprofen (Advil/Motrin) and Aspirin



Action of Aspirin (ASA) - Answer inactivation of Cox-1 and Cox-2; inhibits formation of prostaglandins



Indication for Aspirin - Answer Suppression of inflammation;

Analgesia;

Antipyretic for adults only;

Dysmenorrhea;

Suppression of platelet aggregation;

Prevention of colorectal cancer



Adverse effects of Aspirin - Answer GI effects: Gastric ulceration, perforation



Bleeding

Renal impairment

Salicylism

Reye's syndrome

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