Dantrolene sodium counteracts the symptoms of malignant hyperthermia by
inhibiting calcium release in striated muscle cells.
The following anaesthetic drugs have been linked to malignant hyperthermia: -
ANSWER: Halothane
Pretreatment with dantrolene for most MH-vulnerable patients is not suggested.
Because of the cost of keeping dantrolene in stock, it is fair for nearby
institutions to share a supply of dantrolene. - Answer: false
When taking a preoperative history, ask about any personal history of MH or
adverse reactions to anaesthesia, as well as any family history of unexplained
deaths after general anaesthesia.
C) Family history or personal experience with myopathy D) All of the above
Answer: all of the above.
Which of the following is regarded safe for MH-susceptible patients? -
ANSWER A) general anaesthesia using non-triggering drugs
There are three options for anaesthesia: regional, local, or all of the above.
Answer: all of the above.
The reconstitution and administration of dantrolene sodium is extremely labor-
consuming. To prepare for injection, add 60 ml of sterile water (USP) without
bacteriostatic agents to each vial.
C) Shake vigorously for 2-3 minutes per vial. D) All of the above.
Answer: all of the above.
After an uncomplicated ambulatory surgery, MH vulnerable individuals should
be monitored for: - ANSWER: One to two hours before discharge
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