AOCNP Test Review 2024 Exam Questions With Correct Answers.
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AOCNP
Institution
AOCNP
AOCNP Test Review 2024 Exam Questions
With Correct Answers.
Treatments that place individuals at increased risk for infection - answerChemotherapy treatments
including high-dose cyclophosphamide, doxorubicin, docetaxel, or alemtuzumab.
Colony stimulating factors (CSF) - answer**GM-CSF : growth ...
AOCNP Test Review 2024 Exam Questions
With Correct Answers.
Treatments that place individuals at increased risk for infection - answer✔Chemotherapy treatments
including high-dose cyclophosphamide, doxorubicin, docetaxel, or alemtuzumab.
Colony stimulating factors (CSF) - answer✔**GM-CSF : growth factor for hematopoietic stem cells and
granulocyte/monocytes
**M-CSF (macrophage): essential for macrophage production
**G-CSF (granulocyte) :essential for neutrophils
**Erythropoietin (EPO): growth factor for RBC
Filgrastim (Neupogen)
Pegfilgrastim (Neulasta)
Tbo-filgrastim (Granix) - answer✔Common side effects: mild to moderate bone pain
Used to patients at risk of experiencing treatment induced neutropenia
Major benefit: reducing the possibility of myelosuppression and permitting the continuation of
therapeutic chemotherapy doses
Filgrastim (Neupogen) - answer✔Dose: 5 µg per kilogram per day. Begin 24 to 72 hours after completion
of chemotherapy and continue through the post nadir period.
Pegfilgrastim (Neulasta) - answer✔That was: 6 mg per cycle. Again 1 to 3 days post chemotherapy.
Administer as a single 6 mg injection once per cycle. Do not administer in the period beginning 14 days
before until 24 hours after administration of chemotherapy.
Antimicrobial prophylaxis for infection - answer✔Low risk: no prophylaxis Recommended unless the
patient has prior herpes simplex virus episode.
Fungal: consider fluconazole during neutropenia and if mucositis is anticipated
Viral: during neutropenia and at least 30 days after transplantation
High risk:
Bacterial: consider fluoroquinolone
Fungal: consider fluconazole or other anti-fungal agent
Viral: during neutropenia and at least 30 days after transplantation
Graft versus host disease: penicillin andtrimethroprim/sulfamethoxazole (tmp/smx) Or equivalent for
allogenic heamatopoetic Stem cell transplant recipients
Alemtuzumab: TMP/SMX
Complete diagnostic work up for neutropenic fever - answer✔Blood cultures: bacterial, viral, and fungal
BUN, electrolytes, and creatinine
Chest x-ray
CBC and differential
Liver function test
Pulse oximetry
Site-specific cytology and cultures
Urinanalysis
ANC calculation - answer✔WBC x [(% segs + % bands)/100]
aplastic anemia - answer✔a normocytic-normochromic type of anemia characterized by the failure of
bone marrow to produce red blood cells
hemolytic anemia - answer✔characterized by an inadequate number of circulating red blood cells due to
the premature destruction of red blood cells by the spleen
deficiency anemia - answer✔anemia caused by lack of necessary nutrients
B12, folate, and iron
Anemia # of RBC/ MCV - answer✔Microcytic. Normocytic. Macrocyctic.
Microcytic anemia with ↓ serum iron, ↓ total iron-binding capacity (TIBC), and normal or ↑ ferritin. -
answer✔cells smaller than normal
Normal platelet range - answer✔150,000-400,000/mm3
Thrombocytopenia - answer✔low platelet count, Less than 100
Decrease platelet production can occur in patients with cancer as the result of colon tumor invasion of
the bone marrow or spleen, bone marrow suppression, aplastic anemia
Herbal agents that can cause thrombocytopenia - answer✔Ginkgo biloba, garlic, ginger, turmeric
Medication that can cause anemia - answer✔Aspirin
Heparin
Digoxin
Thiazide diuretics
NSAIDS
PHENYTOIN
quinine
Abx
Tricyclic anti depressant
Benzene
Interleukin-11 (platelet growth factor) - answer✔Oprelvekin. Thrombocytopenia related to
chemotherapy
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