©THEBRIGHT EXAM SOLUTIONS
11/6/2024 12:22 AM
AOCNP Exam Questions With Correct
Answers.
Side effects of oxaliplatin - answer✔Neuropathy
Cumulative risk for Infusion reaction
Cold sensitivity
Side effects of avastin - answer✔HTN
Nasal perforation
Delayed wound healing
Proteinuria
Side effects of cetuximab - answer✔Acne form rash w/ risk of infection
Hypersensitivity
Alopecia, hair changes, long eyelashes
Nail changes (paronychia) and fissures
Nanotechnology - answer✔the branch of engineering that deals with things smaller than 100
nanometers (especially with the manipulation of individual molecules)
EGFR class effects - answer✔Inflammatory rash
Diarrhea
Hypomagnesemia
Interstitial lung disease
Examples of antimetabolites - answer✔Fluorouracil, Methotrexate, gemzar, cytarabine, capcitabine
Side effects of antimetabolites - answer✔Bone marrow suppression
Mucositis- stomatitis, diarrhea
Examples of alkylating agents - answer✔Cyclophosphamide
, ©THEBRIGHT EXAM SOLUTIONS
11/6/2024 12:22 AM
Cisplatin
Side effects of alkylation agents - answer✔Bone marrow suppression
Damage to reproductive organs
examples of mitotic inhibitors - answer✔Taxol
Taxotere
Vincristine
Side effects of mitotic inhibitors - answer✔Neuropathy
Many are vesicants
examples of antitumor antibiotics - answer✔Doxorubicin
Bleomycin
Side effects of antitumor antibiotics - answer✔Bone marrow suppression
Damage to cardiac myocytes
Most are vesicants
2 portions of monoclonal antibodies - answer✔The fab portion
The FC portion
Fab portion - answer✔antigen-binding portion of antibody. Specific for each antigen.
Fc portion - answer✔Calls and binds immune effector cells to the antigen to kill it
Principle ways immune cells kill antigen containing cells? - answer✔ADCC
CDC
Albumin measures - answer✔Protein stores
What does serum prealbumin measure? - answer✔Protein depletion
What does serum transferrin measure? - answer✔Reflects the body's ability to make serum protein
Recommended medications for low risk emetogenic chemo - answer✔-it is recommended to use a
single agent such as steroid, Regina, compazine, or 5-HT3 antagonist
Recommended medications for moderate risk emetogenic chemo - answer✔- combo 5-HT3 antagonist,
steroid, +\- NK1 antagonist, +\- anxiolytic
, ©THEBRIGHT EXAM SOLUTIONS
11/6/2024 12:22 AM
Recommended medications for high risk emetogenic chemo - answer✔combo 5-HT3 antagonist, steroid,
and NK1 antagonist, +\- anxiolytic
Examples of 5-HT3 antagonists: - answer✔Ondansetron, Dolasetron, Granisetron, Palonosetron,
Alosetron
Examples of NK1 receptor antagonists - answer✔Aprepitant
Fosaprepitant
Primary constipation induced medication - answer✔Opioids
Job of small intestine - answer✔absorb nutrients from food
job of large intestine - answer✔absorb water; finish absorbing vitamins
Chemo agent most commonly associated with diarrhea - answer✔5 FU
Chemo agents most commonly associated with constipation - answer✔Vinca alkaloids
- vincristine
- vinorelbine
- vinblastine
Loperamide package instructions - answer✔4mg after first loose stool
2 mg After each diarrhea
Max 16mg/day
Aggressive loperamide therapy - answer✔4 mg after initial episode of diarrhea
2mg q 2 hrs until diarrhea free for 12 hrs
Treatment of c diff - answer✔
Frontal lobe in brain controls? - answer✔Personality
Intellect
Judgement
Mood
Affect
Parietal lobe in brain controls? - answer✔Sensory perception
spatial relations
11/6/2024 12:22 AM
AOCNP Exam Questions With Correct
Answers.
Side effects of oxaliplatin - answer✔Neuropathy
Cumulative risk for Infusion reaction
Cold sensitivity
Side effects of avastin - answer✔HTN
Nasal perforation
Delayed wound healing
Proteinuria
Side effects of cetuximab - answer✔Acne form rash w/ risk of infection
Hypersensitivity
Alopecia, hair changes, long eyelashes
Nail changes (paronychia) and fissures
Nanotechnology - answer✔the branch of engineering that deals with things smaller than 100
nanometers (especially with the manipulation of individual molecules)
EGFR class effects - answer✔Inflammatory rash
Diarrhea
Hypomagnesemia
Interstitial lung disease
Examples of antimetabolites - answer✔Fluorouracil, Methotrexate, gemzar, cytarabine, capcitabine
Side effects of antimetabolites - answer✔Bone marrow suppression
Mucositis- stomatitis, diarrhea
Examples of alkylating agents - answer✔Cyclophosphamide
, ©THEBRIGHT EXAM SOLUTIONS
11/6/2024 12:22 AM
Cisplatin
Side effects of alkylation agents - answer✔Bone marrow suppression
Damage to reproductive organs
examples of mitotic inhibitors - answer✔Taxol
Taxotere
Vincristine
Side effects of mitotic inhibitors - answer✔Neuropathy
Many are vesicants
examples of antitumor antibiotics - answer✔Doxorubicin
Bleomycin
Side effects of antitumor antibiotics - answer✔Bone marrow suppression
Damage to cardiac myocytes
Most are vesicants
2 portions of monoclonal antibodies - answer✔The fab portion
The FC portion
Fab portion - answer✔antigen-binding portion of antibody. Specific for each antigen.
Fc portion - answer✔Calls and binds immune effector cells to the antigen to kill it
Principle ways immune cells kill antigen containing cells? - answer✔ADCC
CDC
Albumin measures - answer✔Protein stores
What does serum prealbumin measure? - answer✔Protein depletion
What does serum transferrin measure? - answer✔Reflects the body's ability to make serum protein
Recommended medications for low risk emetogenic chemo - answer✔-it is recommended to use a
single agent such as steroid, Regina, compazine, or 5-HT3 antagonist
Recommended medications for moderate risk emetogenic chemo - answer✔- combo 5-HT3 antagonist,
steroid, +\- NK1 antagonist, +\- anxiolytic
, ©THEBRIGHT EXAM SOLUTIONS
11/6/2024 12:22 AM
Recommended medications for high risk emetogenic chemo - answer✔combo 5-HT3 antagonist, steroid,
and NK1 antagonist, +\- anxiolytic
Examples of 5-HT3 antagonists: - answer✔Ondansetron, Dolasetron, Granisetron, Palonosetron,
Alosetron
Examples of NK1 receptor antagonists - answer✔Aprepitant
Fosaprepitant
Primary constipation induced medication - answer✔Opioids
Job of small intestine - answer✔absorb nutrients from food
job of large intestine - answer✔absorb water; finish absorbing vitamins
Chemo agent most commonly associated with diarrhea - answer✔5 FU
Chemo agents most commonly associated with constipation - answer✔Vinca alkaloids
- vincristine
- vinorelbine
- vinblastine
Loperamide package instructions - answer✔4mg after first loose stool
2 mg After each diarrhea
Max 16mg/day
Aggressive loperamide therapy - answer✔4 mg after initial episode of diarrhea
2mg q 2 hrs until diarrhea free for 12 hrs
Treatment of c diff - answer✔
Frontal lobe in brain controls? - answer✔Personality
Intellect
Judgement
Mood
Affect
Parietal lobe in brain controls? - answer✔Sensory perception
spatial relations
