Loss of hypothalamic neurons that produce the hypocretin
Conventional means to confirm Narcolepsy diagnosis
nocturnal polysomnogram and MSLT
Features of Hypersomnolence disorder that distinguish it from Narcolepsy
Labs do not indicate Narcolepsy
Longer and less fragmented nocturnal sleep,
Greater difficulty waking up,
More continuous daytime sleepiness (rather than more discrete "sleep attacks"
in narcolepsy),
Longer and less refreshing daytime sleep episodes,
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