MSN 611 Final Exam with Complete
Solutions
Food-drug or drug-drug interactions with antibacterial medications are usually addressed by
Correct Ans-Separating administration times
Which of the following statements is accurate regarding multiple drug combination treatment
for tuberculosis? Correct Ans-It has decreased the risk of resistance
Which of the following describes IFN-B? Correct Ans-Used to treat multiple sclerosis
Which of the following protozoal diseases is associated with as many as 500 milliion new
infections and 2 million deaths annually worldwide? Correct Ans-Malaria
Systemic chemotherapy that is given prior to surgery or radiation serves to Correct Ans-
increase effectiveness of local treatment
How is tumor lysis syndrome managed in leukemia patients? Correct Ans-IV hydration
Acrolein is a toxic metabolite of cyclophosphamide and ifosfamide that can cause? Correct
Ans-Hemorrhagic cystitis
Which category of antineoplastic drugs offers an alterantive when traditional treatments fail?
Correct Ans-Immunosuppressants
Topoisomerase inhibitors target enzymes that control changes in DNA? Correct Ans-structure
, What effects do cholinesterase inhibitors have on sinoatrial and atrioventricular nodes?
Correct Ans-Vagotonic
How do "mixed acting" sympathomimetic drugs work? Correct Ans-They directly activate the
release of norepinephrine while also indirectly causing a release of norepinephrine
For which disease are GABA-derivative antispasmodic agents used effectively to control muscle
spasm? Correct Ans-Multiple sclerosis
What is the FDA-approved use for belladonna? Correct Ans-Moderate to severe pain
associated with ureteral spasms not responsive to non-narcotic analgesics
After the first dose of warfarin how much time is required for therapeutic effects to begin?
Correct Ans-5 to 7 days
Function of plasmin Correct Ans-Breaking cross links between fibrin molecules and
disrupting structural integrity, dissolve blood clots
Most antihemorrhagic agents are derived from? Correct Ans-human sources
Which of the following is the primary causative factor for Crohn's disease? Correct Ans-
etiology is unknown at this time
FDA-approved treatment for thrombocytopenia? Correct Ans-Oprelvekin
Hypertension medication preferentially considered for African Americans Correct Ans-
Thiazide type diuretics
Drug of choice for treating hypertension in Correct Ans-methylevadopa
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