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PHAR 100 - Module 1 Exam Questions and Answers
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PHAR 100 - Module 1 Exam Questions and Answers
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PHAR 100 - Module 1 Exam Questionsand Answers
drugs ii- iiAnswers ii-any iisubstance iireceived iiby iia iibiological iisystem iithat iiis iinot iifor
iinutritional iipurposes
pharmacology ii- iiAnswers ii-science iiof iidrugs iiincluding iitheir iiuses, iieffects, iiand iimodes
iiof iiaction
Influence iiof iipoison: iiCurare ii- iiAnswers ii-Used iias iipoison: iiindigenous iipeople iiof iithe
iiamazon iiused iito iidip iitheir iibows iiin iiit iibecause iiit iicaused iiparalysis iiand iideath
Used iias iia iidrug: iiused iiby iianesthesiologists iito iirelax iia iimuscle iiduring iisurgery
influence iiof iipoison: iiergot ii- iiAnswers ii-Poison: iipoison iifungus iithat iigrows iiin iibread
iiand iikilled iia iibunch iiof iipeople iiin iithe iimedieval iitimes
drug: iiused iito iiprevent iimigraines iibecause iiit iiconstricts iiblood iiflow
Drugs iiacting iion iithe iibrain: iiReserpine iiand iiChlorpromazine ii- iiAnswers ii-discovery:
iithe iiextracts iiof iia iirauwolfia iiplant iiwere iiused iiby iiIndian iimedicine iito iireduce iianxiety
iiand iiblood iipressure
therapeutic iiuses: iichlorpromazine iiis iipreferred iito iibe iiused iifor iimental iipatients iithat
iireserpine iibecause iiits iieasier iito iidose iiit iicorrectly. iiConverts iianxious iitense iipeople
iiinto iicalm iipeople
Drugs iiacting iion iithe iibrain: iiLysergic iiand iidiethylamide ii(LSD) ii- iiAnswers ii-discovery:
iia iiSwiss iipharmaceutical iiwas iitrying iito iimake iiproducts iifrom iiergot
contribution iito iipharmacology: iithe iidiscovery iiof iithe iipsychedelic iieffects iiof iiLSD
iisupported iithe iiidea iithat iisome iimental iiillnesses iimight iibe iidue iito iichemicals iiin iithe
iibrain
Drugs iiacting iion iithe iibrain: iiAnesthetics ii- iiAnswers ii-Nitrous iiOxide ii(laughing iigas): iia
iichemist iiwas iigiving iidemonstrations iiin iithe ii1840s, iiand iithis iione iiman iiwas iion iithe
iigas iiand iigashed iihis iileg iibut iifelt iino iipain. iia iidentist iiin iithe iicrowd iistarted iiusing iiit
iifor iipatients
Ether: iisimilar iiproperties iito iilaughing iigas
1. iidrug iidiscovery ii- iiAnswers ii-- iiidentify iia iitarget ii(receptor)
- iionce iia iicompound iiis iifound iithat iibinds iiwell iito iia iireceptor, iiits iieffects iion iithe
iimolecular, iicellular, iiand iianimal iilevel iiare iitested
- iiif iiit iishows iipromise, iiit'll iigo iion iito iithe iipre-clinical iitrial
, 2. iiPre-clinical iistudies ii- iiAnswers ii-- iiIS iiIT iiSAFE iiAND iiEFFECTIVE?
- iithis iitesting iihappens iibefore iiany iitesting iion iihumans ii
-Toxicology iistudies iiand iiPharmacological iistudies
Toxicology iistudies ii- iiAnswers ii-- iia iipre-clinical iistudy
- iidetermines iiif iithe iidrug iihas iiany iiadverse iieffects iion iiother iiorgans
- iiall iidrugs iiare iitoxic iiat iisome iilevel ii
-expensive iiand iican iitake iiup iito ii6 iiyears
Pharmacological iistudies ii- iiAnswers ii-- iia iipre-clinical iistudy
- iidetermines iithe iidetailed iimechanisms iiof iithe iinew iidrug
3. iiClinical iitrial: iiInitial iiSteps ii- iiAnswers ii-to iitest iion iihumans, iithe iifollowing iiis
iirequires: ii
- iishow iiproof iithat iiit iiwas iisafe iifrom iitesting iion iianimals
- iimethodology iiof iithe iiproposed iiclinical iitrial iiis iirequired
- iiyour iidrug iineeds iito iibe iievaluated iiby iiother iiscientists
4. iiPhase ii1 iiClinical iiTrial ii- iiAnswers ii--conducted iion iihealthy iipeople
- iicarefully iievaluates iithe iieffect iiof iithe iidrug
- iitests iidosages iiand iitolerability ii
-doesn't iiassess iithe iiefficacy
5. iiPhase ii2 iiClinical iiTrial ii- iiAnswers ii-- iiconducted iion iithe iipeople iiwith iithe iidisease
iithe iidrug iiaims iito iifix
- iitests iiif iithe iidrug iiis iieffective iion iitreating iithat iidisease
- iipaying iicareful iiattention iito iithe iisafety iiof iithe iidrug
6. iiPhase ii3 iiClinical iiTrial ii- iiAnswers ii-- iitest iithe iidrug iion iia iilarge ii# iiof iipeople
- iilongest iiclinical iitrial iistage
- iidone iiin iimultiple iicities iito iikeep iiit iidiverse
- iimost iiexpensive iipart iioff iidrug iitrials ii
-determines iisafety iiand iieffectiveness
Target iiPopulation ii(Phase ii3 iiClinical iiTrial) ii- iiAnswers ii-- iia iigroup iiwho iithe iidrug iiis
iimeant iifor
Study iipopulations ii(Phase ii3 iiClinical iiTrial) ii- iiAnswers ii-- iirandomized iiallocation
iimakes iisure iithere iiis iian iiequal iichance iiof iibeing iiin iithe iicontrol iior iitreatment iigroup
ii(ensures iidiversity)
Treatment iigroup ii(Phase ii3 iiClinical iiTrial) ii- iiAnswers ii-will iiget iithe iinew iidrug iion iitrial
Control iigroup ii(Phase ii3 iiClinical iiTrial) ii- iiAnswers ii-will iiget iithe iiplacebo iidrug iior iithe
iigold iistandard iidrug
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