Which of the following statements regarding the development of the CNS in the
first two years of life is correct?
A Myelination of the CNS is complete
B The forebrain, midbrain and spinal cord are equally developed
C Cortical synpatic density is at its highest
D The motor cortex develops ahead of the sensory cortex
E The gonadotropin-gonadal axis is not yet functioning - ANSWERS-D
QUESTION 2
FDA-approved use of deep brain stimulation for treatment-resistant OCD (under
the humanitarian device exemption mechanism) involves stimulation of what brain
regions?
A Caudate nuclues
B Orbital frontal cortex
C Subthalamic nucleus
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D Subgenual cingulate gyrus
E Anterior limb of the internal capsule - ANSWERS-E
QUESTION 3
What region of the frontal lobes is most closely associated with working memory?
A Orbitofrontal
B Frontal operculum
C Inferior mesial frontal
D Dorsolateral prefrontal
E Ventromedial prefrontal - ANSWERS-D
QUESTION 4
An 82-year-old pt presents with severe memory loss, impaired social judgement,
restricted interests and inability to perform activities of daily living independently.
The best combination therapy to reduce decline in attention and global functioning
would be Donepezil plus a medication with what MOA?
A Dopamine agonist
B Cholinesterase inhibition
C Inhibition of serotonin reuptake
D Enhancement of GABA receptor
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E Modulation of glutamate transmission - ANSWERS-E
QUESTION 5
Which of the following symptoms is most suggestive of BPPV?
A Tinnitus following a viral infection
B Room spinning associated with dysarthria and facial droop
C Severe dizziness with rolling over in bed and tilting head back
D Lightheadedness and progressive hearing loss and gait imbalance
E Unsteadiness accompanied by low frequency tinnitus with hearing loss -
ANSWERS-C
QUESTION 6
Which of the following augmentation agents has the best evidence for efficacy in
patient with OCD who have inadequate response to SSRI?
A Lithium
B Bupropion
C Quetiapine
D Olanzapine
E Aripiprazole - ANSWERS-E
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QUESTION 7
What is the term for clusters of alleles that are in linkage disequilibrium and
inherited as a single unit?
A Haplotype
B Phenotype
C Polymorphism
D Simple tandem repeat
E Copy number variation - ANSWERS-A
QUESTION 8
The neural tube is formed from which of the following?
A Somites
B Ectoderm
C Notochord
D Endoderm
E Mesoderm - ANSWERS-B
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