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AOCNP Questions and Correct Verified Answers

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Side effects of oxaliplatin Neuropathy Cumulative risk for Infusion reaction Cold sensitivity Side effects of avastin HTN Nasal perforation Delayed wound healing Proteinuria Side effects of cetuximab Acne form rash w/ risk of infection Hypersensitivity Alopecia, hair chang...

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  • November 15, 2024
  • 37
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • AOCNP
  • AOCNP
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AOCNP Questions and Correct Verified
Answers
Side effects of oxaliplatin


✓ Neuropathy

✓ Cumulative risk for Infusion reaction

✓ Cold sensitivity




Side effects of avastin


✓ HTN

✓ Nasal perforation

✓ Delayed wound healing

✓ Proteinuria




Side effects of cetuximab


✓ Acne form rash w/ risk of infection

✓ Hypersensitivity

✓ Alopecia, hair changes, long eyelashes

✓ Nail changes (paronychia) and fissures




Nanotechnology




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✓ the branch of engineering that deals with things smaller than 100 nanometers
(especially with the manipulation of individual molecules)




EGFR class effects


✓ Inflammatory rash

✓ Diarrhea

✓ Hypomagnesemia

✓ Interstitial lung disease




Examples of antimetabolites


✓ Fluorouracil, Methotrexate, gemzar, cytarabine, capcitabine




Side effects of antimetabolites


✓ Bone marrow suppression

✓ Mucositis- stomatitis, diarrhea




Examples of alkylating agents


✓ Cyclophosphamide

✓ Cisplatin




Side effects of alkylation agents




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✓ Bone marrow suppression

✓ Damage to reproductive organs




examples of mitotic inhibitors


✓ Taxol

✓ Taxotere

✓ Vincristine




Side effects of mitotic inhibitors


✓ Neuropathy

✓ Many are vesicants




examples of antitumor antibiotics


✓ Doxorubicin

✓ Bleomycin




Side effects of antitumor antibiotics


✓ Bone marrow suppression

✓ Damage to cardiac myocytes

✓ Most are vesicants




2 portions of monoclonal antibodies



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✓ The fab portion

✓ The FC portion




Fab portion


✓ antigen-binding portion of antibody. Specific for each antigen.




Fc portion


✓ Calls and binds immune effector cells to the antigen to kill it




Principle ways immune cells kill antigen containing cells?


✓ ADCC

✓ CDC




Albumin measures


✓ Protein stores




What does serum prealbumin measure?


✓ Protein depletion




What does serum transferrin measure?


✓ Reflects the body's ability to make serum protein




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