Exam (elaborations)
BIL 255 EXAM 4 QUESTIONS AND VERIFIED ANSWERS
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BIL 255 EXAM 4 QUESTIONS AND VERIFIED ANSWERS....
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Which of the following transporters mediates primary active transport whentransporting the solutes in the directions indicated? The concentration of both
solutes (shown as small circles and squares) is higher outside of the cell.
A)
B)
C)
D)
E)*****
After release into the synaptic cleft, the neurotransmitter dopamine is actively
taken up by the cells via specific dopamine transporters. The drug cocaine
interferes with this process and is therefore called a reuptake inhibitor. The
inhibition of the transporter at a certain cocaine concentration is qualitatively
represented in the following graph. Based on this graph, which of the following
describes the effect of cocaine on the kinetics of dopamine reuptake by the
transporter?
A) In the presence of cocaine, the maximal rate of transport (Vmax) is
unaffected, but the apparent affinity of the transporter for dopamine is
reduced.******
B) In the presence of cocaine, the maximal rate of transport (Vmax) is reduced,
but the apparent affinity of the transporter for dopamine is unaffected.
C) In the presence of cocaine, the maximal rate of transport (Vmax) is
enhanced, but the apparent affinity of the transporter for dopamine is
unaffected.
D) In the presence of cocaine, both the maximal rate of transport (Vmax) and
the apparent affinity of the transporter for dopamine are enhanced.
,E) In the presence of cocaine, both the maximal rate of transport (Vmax) and the
apparent affinity of the transporter for dopamine are unaffected, but the
transporter is nevertheless inhibited.
Dopamine is a neurotransmitter involved in the reward pathways in the brain,
and its decreased activity has been associated with diseases such as Parkinson's
disease and attention-deficit/hyperactivity disorder (ADHD). Which of the
following drugs is NOT a likely candidate to treat these diseases?
A) Methylphenidate, a dopamine reuptake inhibitor
B) Amphetamine, a dopamine-releasing agent that triggers the release of
dopamine into the synaptic cleft
C) Carbidopa, which enhances the availability of the dopamine synthesis
precursors in the brain
D) Forskolin, a sensitizer of dopamine receptors
E) Chlorpromazine, a dopamine antagonist that binds to and inhibits dopamine
receptors******
Phospholipids with short or unsaturated fatty acyl chains
A) decrease membrane fluidity
B) increase membrane fluidity******
C) cause bio-membranes to become thicker
D) allow hydrophilic molecules to diffuse across the lipid bilayer.
Movement of phospholipids from one leaflet to the other?
A) occurs routinely
B) requires cholesterol
C) requires flippases*****
D) is impossible
Three phospholipids X, Y, and Z are distributed in the plasma membrane as
indicated in the figure. Which of these phospholipids are not moved by a
flippase?
, A) X only
C) X and Y
B) Z only******
D) Y and Z
Transepithelial glucose transport uses a symport to transport glucose up a
concentration gradient by
A) coupling glucose transport to proton movement.
B) coupling glucose transport to Na+ movement.******
C) coupling glucose transport to Ca2+ movement.
D) coupling glucose transport to Cl- movement.
Which of the following statements is correct regarding ATP driven pumps??
A) ATP driven pump have ion selectivity filters
B) Eukaryotic cells contain a variety of ATP driven pumps including Na+/K+
ATPase, Ca++ ATPase and H+ ATPase*****
C) All ATP driven pumps are found in the plasma membrane
D) Inhibition of the Na+/K+ ATPase would result in [K+in]>[K+out]
For a nerve cell at its resting potential (-70 mV), the forces acting on potassium
ions (K+) are
A) none: K+ ions do not move at the resting potential.
B) an electrical gradient, pulling K+ inward, and a chemical gradient, pushing
K+ inward.
C) an electrical gradient, pushing K+ outward, and a chemical gradient, pulling
K+ inward.
D) an electrical gradient, pulling K+ inward, and a chemical gradient, pushing
K+ outward.*******
E) an electrical gradient, pushing K+ outward, and a chemical gradient, pushing
K+ outward.
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