NURS 5315 UTA Exam 2 Questions and
Answers
HIV iiEIA ii(3rd iigeneration iiimmunoassay) ii- iiAnswers ii-can iiuse iiurine, iisaliva, iior iiserum
ii(most iiaccurate), iineed iito iiwait iiuntil ii12 iiweeks iipost iiexposure iito iisee iiantibodies,
ii>99% iiaccurate
4th iigeneration iiimmunoassay- ii"gold iistandard"
measures iiP24 iiantigen
can iitest ii10 iidays iipost iiexposure
Mast iicell ii- iiAnswers ii-Cellular iibags iiof iigranules iilocated iiin iiloose iiconnective iitisssue
iiclose iito iiblood iivessels. iiActivation iiinitiates iiinflammatory iiprocess.
Histamine ii- iiAnswers ii-Causes iivasodilation, iiincreases iivascular iipermeability,
iiincreases iiblood iiflow iito iithe iisite iiof iiinjury- iicauses iierythema iiand iiswelling.
Cytokines ii- iiAnswers ii-Soluble iifactors iithat iicontribute iito iithe iiregulation iiof iiinnate iior
iiadaptive iiresistance iiby iiaffecting iiother iineighboring iicells. iiCan iibe iipro-inflammatory
iior iianti-inflammatory. iiCan iireact iiquickly iior iibe iimore iidelayed.
Leukotrines ii- iiAnswers ii-Released iiwhen iimast iicells iidegranulate, iiprolong iithe
iiinflammatory iiprocess. iiCause iivasodilation, iiattract iineutrophils, iimonocytes, iiand
iieosinophils.target iiof iiinhibition iifor iisingular.
Prostaglandins ii- iiAnswers ii-Released iiwhen iimast iicells iidegranulate, iiare iiproduced iiby
iithe iiarachidonic iipathway. iiCause iivasodilation, iiplatelet iiaggregation iiat iisite iiof iiinjury,
iipain, iiand iifever.
Chemotactic iifactors ii- iiAnswers ii-Biochemical iisubstance iithat iiattracts iileukocyte iito
iithe iisite iiof iiinflammation
Neutrophils ii- iiAnswers ii-Predominant iileukocyte iiat iiwork iiduring iithe iiearly iistages iiof
iiacute iiinflammation
Monocytes ii- iiAnswers ii-Become iimacrophages iiwhen iientering iithe iitissue, iiresponsible
iifor iipresenting iiantigens iito iithe iiCD4 iicell iiwhich iitriggers iiT-cell iiimmunity iiand iiB-cell
iiimmunity.
Releases iiadditional iicytokines iiIL1, iiIL6, iiTNF.
Cytokine iiIL1 iifunction ii- iiAnswers ii-Causes iifever, iiactivates iiphagocytes ii&
iilymphocytes iiand iialso iiincreases iithe iirelease iiof iiIL6a
, Cytokine iiIL6 iifunction ii- iiAnswers ii-Stimulates iiproduction iiof iiacute iiphase iireactants
iiand iipromotes iigrowth iiand iistimulation iiof iiRBCs
Cytokine iiTNF iifunction ii- iiAnswers ii-Causes iifever, iiincreases iisynthesis iiof
iiproinflammatory iiproteins iiby iiliver, iicauses iimuscle iiwasting, iiinduces iithrombosis
Cytokine iigrowth iifactor iifunction ii- iiAnswers ii-Promotes iiproduction iiand iimaturation iiof
iineutrophils
Complement ii- iiAnswers ii-Functions iiinclude iibacterial iilysis, iivasodilation iiand
iiincreased iivascular iipermeability, iitriggers iimast iicell iidegranulation, iichemotaxis, iiand
iiopsonization.
Kinin ii- iiAnswers ii-Converted iito iibradykinin iiwhich iiis iiresponsible iifor iipain iiand
iichemotaxis, iiand iiit iiincreases iivascular iipermeability iiand iivasodilation.
Coagulation iicascade ii- iiAnswers ii-Factor iiXII iiactivates iikinin. iiFunction iiis iito iiform
iifibrin iimesh iito iistop iibleeding iiand iitrap iimicro iiorganisms.
COX1 ii- iiAnswers ii-Prostaglandin iiof iiarachidonic iipathway. iiProvides iigastroprotection,
iiplatelet iiaggregation, iifluid/electrolyte iibalance
COX2 ii- iiAnswers ii-Prostaglandin iiof iiarachidonic iipathway. iiResponsible iifor iipain,
iifever, iirenal iiprotection, iitissue iirepair, iireproduction iidevelopment.
COX2 iiinhibitors- iiclinical iiimplications ii- iiAnswers ii-Protect iigastric iimucosa- iiprevent
iiulcers iiand iibleeding. iiRemoved iifrom iimarket iir/t iicardiac iievents iiexcept iifor iiCelebrex.
iiCan iiimpair iirenal iifunction ii, iimonitor iilabs.
Arachidonic iipathway iipurpose ii- iiAnswers ii-Synthesis iiof iiprostaglandins
Non-selective iiNSAIDS ii- iiAnswers ii-Inhibit iiCOX1 iiand iiCOX2, iirisk iifor iigastric
iiulceration, iiGI iibleeds, iiedema, iirenal iiimpairment
ASA ii- iiAnswers ii-Blocks iiCOX1 iiand iiCOX2, iialso iiinhibits iiThromboxane iiA2 iiand
iiprostaglandins
Corticosteroids ii- iiAnswers ii-Inhibit iiphospholipase iiA2, iipreventing iiformation iiof
iiprostaglandins, iithromboxane iiA2, iiprostacyclin, iiand iileukotrines
Thromboxane ii- iiAnswers ii-Vasoconstriction, iiplatelet iiaggregation
Prostacyclin ii- iiAnswers ii-Vasodilation, iiplatelet iiaggregation ii(most iieffective iione)