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NEUROPSYCHOPHARMACOLOGY DR TAM EXAM 1 | 211 QUESTIONS | WITH ACCURATE SOLUTIONS!!
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NEUROPSYCHOPHARMACOLOGY DR TAM EXAM 1 | 211 QUESTIONS | WITH ACCURATE SOLUTIONS!!
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NEUROPSYCHOPHARMACOLOGY DR TAMEXAM 1 | 211 QUESTIONS | WITH ACCURATE
SOLUTIONS!!
Where are drugs synthesized? Answer - Outside the body (exogenous).
Endogenous chemicals are biochemicals.
What are the three rules to follow biochemical ethics? Answer - 1.Reduce the
pain/suffering of the patient.\n2.Weigh the beneficial effects against the
detrimental to decide. Increase the quality of life.
What is the definition of drug at the physiological\nlevel? Answer - Drugs are
the induction mechanisms for altering the\nphysiological functions of an
animal (or plant).
What is the definition of drug at the neural level? Answer - Drugs are the
chemical signals that turn on (or off)\nspecific neural circuitry.
Regulation of receptors Answer - There are modified in number (long-term)
and sensitivity (short-rapid term via second messengers)
Receptor Subtype Answer - Drug receptor proteins that have different
characteristics in different target tissues.
What is an ionotropic receptor (ionic channel)? Answer - A receptor with a
channel pore that ions can flow through.
,What is the predominant ion in the cell Answer - K+ is the predominant
POSITIVE ion
Na/k pumps what Answer - 3 Na out for every 2 K in
what is the resting potential membrane Answer - -70mv
Main NT for Excitation Answer - Acetyl-choline and Glutamate
Main NT for Inhibition Answer - GABA, Glycine, Y-aminobutyric acid
Function of Na channel Answer - generation of action potential
Function of K channel Answer - return membrane to resting potential
Function of Ca channel Answer - Stimulation of NT release from post synaptic
neuron
Function of Cl Answer -
Drugs plotted on the same graph (dose x pain effectiveness) that reach at the
same y-axis are said to have.. Answer - Same efficacy
What happens to the dose response curve of an agonist when an antagonist is
added. Answer - The dose response curve moves to the right, but still able to
achieve maximum effect, just more of the agonist needed to be applied/added.
Any receptor that is not ionotropic is ___ Answer - Metabotrophic
, An ion channel can either be ___ (+excitory) or ___ (-inhibitory) Answer -
depolarized\nhyperpolarized
Gs proteins ___ the production of chemicals while Gi ___ it Answer -
stimulate\ninhibit
What is a drug action? Answer - molecular/biochemical action at the binding
site
Self-medication can be beneficial or detrimental based on ___ Answer - pre-
existing conditions
What is an inverse agonist? Answer - renders real neurotransmitters useless in
their presence
What is potency? Answer - more potent if small concentration=high effect
Potentiation Answer - Refers to the situation in which the combination of two
drugs produces effects that are great than the sum of their individuals effects
What is efficacy? Answer - how strong an effect is at the synapse level
(measured in %)
What is competitive binding? Answer - binding can be displaced by another
molecule
What does GABA stand for and what is its function? Answer - gamma amino
butric acid\ninhibitor of neurotransmitter
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