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NR565/ NR 565 Midterm Exam Review: Advanced Pharmacology Care of the Fundamentals - Questions and Answers (2024 / 2025) (Verified Answers)- Chamberlain$10.99
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NR565/ NR 565 Midterm Exam Review: Advanced Pharmacology Care of the Fundamentals - Questions and Answers (2024 / 2025) (Verified Answers)- Chamberlain
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NR565/ NR 565
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NR565/ NR 565
NR565/ NR 565 Midterm Exam Review: Advanced
Pharmacology Care of the Fundamentals - Questions and
Answers (2024 / 2025) (Verified Answers)- Chamberlain
Distribution in medication in elderly can be affected in what ways? - ANSWER --
decreased lean mass
-decreased albumin
-decreased body fat ...
NR565/ NR 565 Midterm Exam Review: Advanced
Pharmacology Care of the Fundamentals - Questions and
Answers () (Verified Answers)- Chamberlain
Distribution in medication in elderly can be affected in what ways? - ANSWER --
decreased lean mass
-decreased albumin
-decreased body fat
-slower gastric acidity
-slower absorption results in delayed response
In the elderly decrease albumin and decreased lean mass affects medications how?
- ANSWER -medication binds to protein so decreased protein affects how
medication is absorbed and distributed
In elderly decreased body fat affects medications how? - ANSWER -need fat to
transport medications and some drug metabolism is dependent on body weight
When prescribing medication, we must understand that liver function declines
with age due to.... - ANSWER -decreased blood flow to the liver, decreased
hepatic enzymes
What is the most important cause of adverse drug reactions? - ANSWER -
***overprescribing/polypharmacy
***decreased renal excretion
-high drug dosages (start low & go slow)
-lack of monitoring medications
What can a poor metabolism phenotype do to a metabolism of a drug? - ANSWER
--slow or increase absorption
-slow the metabolism
-keep drug in body longer
-increase toxicity
, How does poor metabolism affect a high or low therapeutic index? - ANSWER --
increase drug toxicity
(example plavix - clots & increased platelets)
Black box warning for Opioids - ANSWER -respiratory depression
Black box warning for Fentanyl - ANSWER -FATAL respiratory depression
Black box warning for Methadone (NP cannot prescribe) - ANSWER -QT interval
prolongation
Black box warning for Codeine - ANSWER --breastfeeding and infant death can
occur
-10% of dose converts to morphine
Black box warning for hydromorphone & oxymorphone (NP cannot prescribe
long acting hydromorphone and oxymorphone) - ANSWER --risk for high abuse &
overdose
-respiratory depression
Black box warning for oxycodone (NP need additional training to prescribe for
chronic pain) - ANSWER --HIGH potential for abuse
-respiratory depression
Meds that require special training for APNs to prescribe are... - ANSWER --
Opioids
-Fentanyl
-Methadone
-Codeine
-Hydromorphone & oxymorphone
-Oxycodone
What are therapeutic uses for morphine? - ANSWER -MODERATE TO SEVERE
PAIN
-acute pain
, -post op/surgical pain
-end of life pain management
-MI
-labor & delivery
-cancer
What are therapeutic uses for Fentanyl? - ANSWER -BREAKTHROUGH PAIN
surgical pain
severe pain
opioid tolerant patients
What are therapeutic uses for codeine? - ANSWER -MILD TO MODERATE
PAIN
cough
What is MME and when to use it? - ANSWER -morphine milligram equivalent
used for overdose(OD)
assess where patient is at in their pain management and monitor them safely
What is the PDPM and when to use it? - ANSWER --database to access to
patient's prescription history of controlled substances used to ensure safe
prescribing to prevent overdosing and polypharmacy
-use prior to starting opioid therapy and during opioid therapy
Renal and hepatic insufficiencies with opioids
1)Codeine - ANSWER -stays in body longer & metabolism is effected
Renal and hepatic insufficiencies with opioids
2) Morphine - ANSWER -neurotoxicity
Renal and hepatic insufficiencies with opioids
3)Oxycodone - ANSWER -overdose
can use with extreme caution and reduction of dosage
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