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WGU D116 Exam: Questions & Complete Solutions (A+)
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WGU D116 Exam: Questions & Complete Solutions (A+)
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WGU D116 Exam: Questions & Complete Solutions (A+)A patient receives a drug that has a narrow therapeutic range. What is the
nurse administering this medication expected to do? Right Ans - Monitor
plasma drug levels
Narrow therapeutic range is more difficult to administer safely because the
difference between MEC and toxic concentration is small
A patient is receiving intravenous gentamicin. A serum drug test reveals toxic
levels. The dosing is correct, and this medication has been tolerated by this
patient in the past.
What is a probable cause of the test result? Right Ans - The pt is taking
another medication that binds to serum albumin
BGentamicin binds to albumin but weakly. In presence of another drug that
binds to albumin, gentamicin can rise to toxic levels in blood stream
What are the components of pharmacokinetics? Right Ans - Absorption,
distribution, metabolism, excretion
Does the volume of distribution increase or decrease as the concentration of a
drug in the blood plasma increases? Right Ans - DECREASES
A patient reports becoming "immune" to a medication because it no longer
works to alleviate symptoms.
The provider recognizes that this decreased effectiveness is likely caused by
what? Right Ans - Desensitization of receptor sites by continual exposure
to the drug
Continual exposure to an agonist would cause the cell to become less
responsive or desensitized
What occurs when a drug binds to a receptor in the body? Right Ans - It
increases or decreases the activity of that receptor
Which pharmacodynamic principle is most correlated with drug toxicity?
Right Ans - Therapeutic index
, Which is calculated by dividing the median toxic dose by the median
efficacious dose
A patient who is taking morphine for pain asks the nurse how a pain
medication can also cause constipation.
What is the nurse's response? Right Ans - It is selective to receptors that
regulate more than one body process
Which statement about food and drug interactions is true? Right Ans -
Some foods can inhibit CYP isoenzymes and alter drug metabolism
Grapefruit inhibits which lowers metabolism of drugs, leading to toxic effects
of drugs
With respect to the cytochrome P450 (CYP) system, what will result in a
higher concentration of a drug? Right Ans - Inhibition of the enzyme
Decreasing enzyme activity leads to decreased metabolism of the drug,
leading to toxic effects of drug
An advanced practice registered nurse (APRN) works in a urology clinic under
the supervision of a physician who does not restrict the types of medications
the APRN is allowed to prescribe. State law does not require the APRN to
practice under physician supervision.
How would the APRN's prescriptive authority be described? Right Ans -
Independent because the prescriptive authority does not require the APRN
work under physician supervision
Which drug requires registration with the Drug Enforcement Administration
(DEA) to prescribe? Right Ans - Chlordiazepoxide
Schedule IV substance
All scheduled substances require the prescriber to be registered with the DEA
True or False
Your DEA registration allows you to prescribe Schedule II and Schedule III
controlled substances for addiction. Right Ans - FALSE
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