Aprepitant (Emend) - answer-Dose: 40mg PO
Frequency: within 3 hours of anesthesia
ETC: neurokinin-1 receptor antagonist; NOT FOR EXISTING NAUSEA
Dexamethasone (Decadron) - answer-Dose: 4 mg IV over 1-4 minutes
Frequency: Single prophylactic use
ETC: glucocorticoid
Dexmedetomidine (Precede...
CAPA – MEDICINE STUDY GUIDE
Aprepitant (Emend) - answer-Dose: 40mg PO
Frequency: within 3 hours of anesthesia
ETC: neurokinin-1 receptor antagonist; NOT FOR EXISTING NAUSEA
Dexamethasone (Decadron) - answer-Dose: 4 mg IV over 1-4 minutes
Frequency: Single prophylactic use
ETC: glucocorticoid
Dexmedetomidine (Precedex) - answer-Dose: 1mcg/kg bolus over 10 minutes
Infusion Rate: 0.2-0.7mcg/kg/hr
Onset: 1-3 minutes
Duration: 3-5 minutes after infusion stopped
ETC: for short-term sedation for mechanical ventilation; alpha-adrenergic agonist
sedative-hypnotic; off label use for pain relief and shivering, use in pediatrics
Diazepam (Valium) - answer-Dose: 2-10mg IV (less that 5mg/minute)
Frequency:
Duration: 1 hour
ETC: burns when given IV; lipid soluble
Diltiazem (Cardizem) - answer-Dose: 0.25mg/kg IV over 2 minutes
Infusion Rate: 5-15mg/hr
Onset: 3 minutes
Duration: 1-10 hours
ETC: for short-term use only (24 hours); for HTN, afib/flutter, SVT
Droperidol (Inapsine) - answer-Dose: 0.625-1.25mg
Frequency: 5-10 minutes
Onset: 3-10 minutes
Duration: 2-4 hours
ETC: dopamine receptor antagonist; contraindicated in parkinson's; need baselines
EKG; BLACK BOX WARNING for torsades; use other antiemetics
Ephedrine - answer-Dose: 5-25mg IV
Onset: 30 seconds
Duration: 10-60 minutes
ETC: peripheral vasopressor, increases heart rate, bronchodilator; adverse reaction
of headache and tachycardia
Esmolol (Brevibloc) - answer-Dose: 500 mcg/kg over 1 min, the infusion 50-300
mcg/kg/min
Onset: Immediate
Duration: 30 minutes
ETC: for SVT, tachy,hypertension
Fentanyl (Sublimaze) - answer-Dose: 12.5-50mcg IV
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