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UNE Biochem Unit 1 questions and answers
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UNE Biochem Unit 1 questions and answers
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UNE Biochem Unit 1 questions andanswers
Which of the following proteins is likely to have quaternary structure?
a. A protein that contains both a-helix and B-sheet secondary structures
b. A large transmembrane protein with seven a-helical domains
c. A small protein consisting of a single amino acid chain
d. A multimeric protein that contains multiple peptide chains - Answers -d. a multimeric
protein that contains multiple peptide chains
As hemoglobin transitions between the T-state and the R-state, which of the following is
broken as oxygen is added?
a. Hydrogen bonding
b. Iron-Nitrogen links
c. Alpha helixes
d. Salt bridges - Answers -d. salt bridges
Myoglobin is a _____ protein. Hemoglobin is a ______ protein.
a. Monomeric, tetrameric
b. Monomeric, monomeric
c. Tetrameric, tetrameric
d. Tetrameric, monomeric - Answers -a. monomeric, tetrameric
Which of the following amino acids would not be commonly found in the middle of an a-
helix?
a. Valine
b. Leucine
c. Proline
d. Tryptophan - Answers -c. proline
Hemoglobin bound to heme is termed a holoprotein. The heme group (or porphyrin ring)
is required for oxygen binding and it is defined as which of the following?
a. Heteroprotein
b. Prosthetic group
c. Apoprotein
d. Holoprotein - Answers -b. prosthetic group
Cleavage of fructose 1,6-bisphosphate to dihydroxyacetone and glyceraldehyde 3-
phosphate is achieved by what class of enzymes?
a. Lyase
b. Ligase
, c. Transferase
d. Hydrolase - Answers -a. lyase
Which of the following proteins will likely be the most stable and have the lowest energy
state?
a. A protein structure with a high content of random coils
b. A protein structure that is mostly a-helices
c. A structure with a high content of B-sheets
d. A protein structure that is made up of nucleotide folds - Answers -c. a structure with
high content B-sheets
Which of the following coenzymes or cofactors would not typically participate in an
activation transfer reaction?
a. NADH
b. Pyridoxal phosphate (PLP)
c. Coenzyme A
d. Thiamine pyrophosphate
e. Biotin - Answers -a. NADH
Heat can be generated in the brown adipose tissue of hibernating mammals. Which of
the following is the most likely mechanism by which this occurs?
a. A decrease in oxygen consumption
b. Increased ATP production by ATP synthase
c. Expression of a protein that uncouples the ETC
d. An increased pH gradient across the inner mitochondrial membrane - Answers -c.
Expression of a protein that uncouples the ETC
The glycerol 3-phosphate shuttle is the major shuttle of most tissues. Which of the
following best describes the transfer of electrons by this shuttle?
a. Electrons are directly transferred from glycerol 3-phosphate and DHAP
b. Electrons are directly transferred from glycerol 3-phosphate to an NAD containing
glycerol phosphate dehydrogenase
c. Electrons are directly transferred from DHAP (dihydroxacetone) to a FAD containing
glycerol phosphate dehydrogenase
d. Electrons are directly transferred from glycerol 3-phosphate to a FAD containing
glycerol phosphate dehydrogenase - Answers -d. Electrons are directly transferred from
glycerol 3-phosphate to a FAD containing glycerol phosphate dehydrogenase
Which of the following is considered a "free radical" in the Q-cycle?
a. QH2 (quinol)
b. Q (quinone)
c. Q- (semiquinone) - Answers -c. Q- (semiquinone)
Succinate is a substrate for which complex in the electron transport chain?
a. Complex IV (Cyt c oxidase)
b. Complex II (Succinate-Q reductase)
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