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Exam (elaborations)

LAT 2024 EXAM QUESTIONS AND ANSWERS GRADED A+

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Exam of 21 pages for the course LAT at LAT (LAT 2024 EXAM)

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  • November 20, 2024
  • 21
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • LAT
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LAT 2024 EXAM

Carl Linnaeus developed a system to classify organisms based on their anatomical
traits called ___________. - answer Taxonomy

The first step in scientific research is to ___________. - answer Define the question to
be investigated,

In the US, who grants approval to market a new drug after several rounds of clinical
trials? - answer Food and Drug Administration

What type of information is usually included in a grant application? - answer Detailed
description of the research goals, scientific basis of the study, thorough review of
relevant literature, any preliminary date and results, all procedures to be performed.

What three entities require that the IACUC ensures the institution and its personnel
comply with all relevant mandates for animal welfare, thus enforcing self-regulation? –
answer USDA, OLAW, and AAALAS International

List three activities that are performed during post-approval monitoring. - answer
Review of animal health records, inspection of animal use areas, and observation of
animals on study.

What information does an institution provide to AAALAC International to describe its
animal research programs and facilities? - answerAnimal care and use policies and
responsibilities; IACUC activities and administration, animal housing, environment, and
management; veterinary medical care; and physical plant.

Who may conduct an unannounced inspection of registered institutions? - answerUSDA
Veterinary Medical Officers

How often must the institution update its registration with the USDA if using AWA-
covered species? - answerEvery 3 years

According to the USDA, satellite facilities are areas of containment outside of a core
facility, or other centrally designated or managed area in which animals are housed for
more than ____________ hours. - answer12

What procedures may be recorded on herd health records for agricultural laboratory
animals? - answerRoutine husbandry and preventative medical procedures such as
vaccinations.

,Publishes the Policy on the Humane Care and Use of Laboratory Animals. -
answerOLAW

Provides peer evaluation of animal care and use programs. - answerAAALAC
International

Describes what a facility must do to comply with the AWA. - answerAWR

Requires compliance with the GLPs. - answerFDA

Registers institutions using species covered by the AWA. - answerUSDA

AWA/AWRs requires a minimum of ________ members on the IACUC, while the PHS
policy requires a minimum of _________ members. - answer3; 5

PHS Policy is enforced by ________. - answerOLAW

AWA/AWRs are enforced by _________. - answerUSDA, APHIS

Which animals are covered under the Animal Welfare Act and Animal Welfare
Regulations? - answerWild mice

How frequently does the Guide specify that the IACUC review the entire animal care
and use program, including an inspection? - answerAt least once a year

What document can be used to meet the requirements for an OLAW semiannual
program evaluation and report? - answerAn AAALAC site visit review

Which organization uses the Guide as one of its standards for the accreditation of
laboratory animal programs? - answerAAALAC International

Which specific state regulations must be met regarding the sale and shipment of dogs?
- answerRabies vaccination requirements

A ______ includes the animals or other entity that is administered a substance. -
answerTest system

The two federal agencies that require compliance with the GLPs are the _______ and
the _______. - answerFDA; EPA

GLP data archives are kept for _____ years after study completion if they support a
research or marketing permit that was not approved, but they are kept for _____ years
after study completion is the study is not submitted for a marketing permit or is
discontinued. - answer5; 2

, The four core values for the ethical treatment of laboratory animals are: - answer1) The
use of animals in research should be scientifically relevant and appropriate.
2) Animals used in research should be maintained in a way that provides them with as
much physical and psychological wellbeing as possible.
3)Animals used in research should not be subjected to unnecessary pain and distress. If
these effects are unavoidable, efforts should be made to minimize the extent and
duration of the pain and distress.
4) If an animal's severe pain cannot be relieved, the animal should be humanely
euthanized.

The cost recovery percentage is a ratio of _____ to _____. - answerrevenue; expenses

What must an animal facility have to legally keep controlled substances? - answerDEA
license

PHS Policy requires that all assurance records related directed to grant applications,
research proposals, and changes in research activities be maintained for how long? -
answer3 years

The administrative requirements for the procurement, storage, use, and disposal of
scheduled drugs are largely specified by which law? - answerThe Controlled Substance
Act

What must an institution housing USDA-covered animals do annually, as required by
the AWR? - answerSubmit a report.

GLP regulations are most likely to be mandated for which type of study? -
answerEnvironmental study

What must a facility create and follow, as required by GLP Regulations? -
answerStandard Operating Procedures

Who is responsible for monitoring a study and ensuring compliance with GLP
Regulations? - answerQuality assurance unit

Which USDA pain category would correspond with experiments, teaching, research, or
tests causing pain or distress to the animals, for which appropriate anesthetic,
analgesic, or tranquillizing drugs were used? - answerCategory D

Which statement regarding private funding sources is FALSE? - answerResearchers
working for private companies do not need to compete for funding.

Who is responsible for appointing members to the IACUC? - answerChief Executive
Officer

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