INBDE Pharmacology Exam Questions with 100% Correct Answers 2024/2025 Latest Update
Which of the following antibiotics may be cross-allergenic with penicillin?
a. neomycin
b. cephalexin
c. erythromycin
d. clindamycin
e. all of the above - Answer- b. cephalexin
Use of prilocaine carrie...
Which of the following antibiotics may be cross-allergenic with penicillin?
a. neomycin
b. cephalexin
c. erythromycin
d. clindamycin
e. all of the above - Answer- b. cephalexin
Use of prilocaine carries the risk of which of the following adverse effects?
a. porphyria
b. renal toxicity
c. gastric bleeding
d. methemoglobinemia - Answer- d. methemoglobinemia
Quinidine is principally used to treat
a. hypertension
b. angina pectoris
c. congestive heart failure
d. supraventricular tachyarrhythmia - Answer- d. supraventricular tachyarrhythmia
An analgesic compound #3 contains how many mg of codeine?
a. 7.5
b. 15
c. 30
d. 60 - Answer- c. 30
Thiazides, which are used in the treatment of hypertension, may require supplemental
administration of
a. sodium
b. chloride
c. calcium
d. potassium - Answer- d. potassium
-Thiazide diuretics can cause low K+ (hypokalemia)
Which of the following is an example of an enteral route of administration?
a. oral
b. submucosal
,c. inhalation
d. subcutaneous
e. intramuscular - Answer- a. oral
-enteral= gastrointestinal route
-subenteral= sublingual, subcutaneous, IM, IV, inhalation, topical
Neostigmine produces its effect by
a. depressing acetylcholinesterase release
b. inhibiting acetylcholinesterase activity
c. increasing the rate of acetylcholine synthesis
d. acting like acetylcholine at ganglionic sites
e. increasing the amount of acetylcholine released from nerve terminals - Answer- b.
inhibiting acetylcholinesterase activity
Tetracycline reduces the effectiveness of concomitantly administered penicillin by
a. reducing absorption of penicillin
b. increasing metabolism of penicillin
c. increasing renal excretion of penicillin
d. increasing binding of penicillin to serum proteins
e. none of the above - Answer- e. none of the above
-Tetracycline= bacteriostatic= slows growth
-Penicillin= bacteriostatic= kills bacteria
You are performing a root canal treatment on a patient who suffers from dental anxiety.
You decide to prescribe Valium pre-operatively. Benzodiazepines produce their anti-
anxiety effects by modulating which of the following neurohumors?
a. GABA
b. glycine
c. dopamine
d. acetylcholine
e. norepinephrine - Answer- a. GABA
You check the medical history for this same patient and notice he is taking Aspirin. Anti-
inflammatory agents, such as aspirin, interfere
with hemostasis by
A. Activating antithrombin
B. Preventing vasoconstriction
C. Inhibiting thrombin generation
D. Inhibiting platelet aggregation
E. Inhibiting polymerization of fibrin - Answer- D. Inhibiting platelet aggregation
-inhibits thromboxane A2
Amides are metabolized by - Answer- liver
Esters are metabolized by - Answer- pseudocholinesterase in plasma
, Local anesthesia: Amides - Answer- have 2 or more "i" in the name
-Lidocaine (2%)
-Bupivicaine (0.5%)
-Articaine (4%) (Septocaine)
-Mepivicaine (2% & 3%) (Carbocaine)
-Prilocaine
which local anesthetic is safest in children? - Answer- Lidocaine
which local anesthetic is NOT safe in children and has the longest duration? - Answer-
Bupivicaine
which local anesthetic causes the least vasodilation and can be packaged without a
vasoconstrictor? - Answer- Mepivicaine (Carbocaine)
which local anesthetic has one ester, is metabolized by both the liver and blood plasma,
and has the shortest duration of action? - Answer- Articaine (Septocaine)
which local anesthetic can cause methemoglobinemia and is contraindicated in patients
with hepatic (liver) disease? - Answer- Prilocaine
Local anesthesia: Esters - Answer- have 1 "i" in the name
-Procaine
-Cocaine
-Tetracaine
-Benzocaine
which local anesthetic causes vasoconstriction? - Answer- Cocaine
Pharmacodynamics = - Answer- what the drug does to the body
Pharmacodynamics:
Local anesthetics are - Answer- sodium channel blockers
-only non-ionized (uncharged/free base) form can penetrate neuron membrane
Pharmacokinetics = - Answer- what the body does to the drug
increased blood flow to the site = - Answer- shorter duration of action
increased lipid solubility/hydrophobicity = - Answer- more potent; longer duration of
action
-more drug can diffuse through the membrane
increased protein binding = - Answer- longer duration of action
-anesthetic has greater attraction to the receptor sites
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