Chamberlain University
NR507 Advanced Pathophysiology
NR 507 Midterm and Final Exam
Course Title and Number: NR507 Advanced Pathophysiology
Exam
Exam Title: NR 507 Exam
Exam Date: Exam 2024- 2025
Instructor: [Insert Instructor’s Name]
Student Name: [Insert Student’s Name]
Student ID: [Insert Student ID]
Examination
180 minutes
Instructions:
1. Read each question carefully.
2. Answer all questions.
3. Use the provided answer sheet to mark your responses.
4. Ensure all answers are final before submitting the exam.
5. Please answer each question below and click Submit when you have completed
the Exam.
6. This test has a time limit, The test will save and submit automatically when the
time expires
7. This is Exam which will assess your knowledge on the course Learning
Resources.
Good Luck!
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NR507 Advanced Pathophysiology 2024-2025
NR 507 Final Exam Review Questions with Correct
Answers | 100% Pass Guaranteed | Graded A+ |
Read All Instructions Carefully and Answer All the
Questions Correctly Good Luck: -
TSH - =Answer>> Increased production and secretion
of thyroid hormone
Luteinizing Hormone (LH) - =Answer>> Ovulation,
progesterone production (in glanulosa cells)
Follicle Stimulating Hormone (FSH) - =Answer>>
Follicle maturation, estrogen production (In Women:
Granulosa Cells, In Men: Sertoli Cells)
B-Lipotropin - =Answer>> Fat breakdown and release
of fatty acids (Corticotropic, from Adipose Cells)
B-Endorphins - =Answer>> Analgesia; may regulate
body temp, food and water intake (Corticotropic,
Adipose cells, brain opioid receptors)
ADH functions - =Answer>> Homeostasis, control
plasma osmolality. Acts of Vasopressin 2 (V2) receptors
of renal tubular cells to increase permeability which
leads to increased water reabsorption into the blood
and production of more concentrated urine, these may
be inhibited by hypercalcemia, prostaglandin E, and
hypokalemia.
Osmoreceptors - =Answer>>
High levels of ADH - =Answer>> Acts on Vasopressin
1 receptors causing vasoconstriction
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ADH secretion is controlled by: - =Answer>>
osmoreceptors of the hypothalamus. Stimulated by
increased plasma osmolality, then ADH secretion is
increased, water is then reabsorbed from the kidney,
and plasma is diluted to its' setpoint osmolality (280
mOsm/kg). ADH has an indirect affect on electrolyte
levels due to increased water reabsorption. Electrolytes
may decrease.
ADH secretion is also increased by changes in
intravascular volume monitored by mechanoreceptors
in left atrium and carotid and aortic arches. Volume
loss through trauma (7%-25%) acts on receptors to
stimulate ADH secretion.
ADH secretion decreased with: - =Answer>> Decrease
in plasma osmolality, increase in intravascular volume,
hypertension, increase in estrogen, progesterone,
angiotensin II levels, and alcohol ingestion
ADH (given as Vasopressin) may help to: - =Answer>>
Increase BP and to achieve hemostasis during volume
loss during shock states.
Oxytocin - =Answer>> Responsible for contraction of
uterus and milk ejection in lactation, and may effect
sperm motility in men. Oxytocin is stimulated by
sucking and mechanical distention of femaile
reproduction tract. Oxytocin binds to myoepithelial cells
in mammary tissues and causes the contraction of
those cells. "let down" reflex
Hormones of Anterior Pituitary - =Answer>> ACTH,
MSH, LH, GH, FSH, and TSH
Anterior Pituitary composed of two main cell types: -
=Answer>> Chromophobes, and chromophils
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Chromophobes appear to be non-secretory, and
Chromophils are secretory cells of the
adenohypophysis.
Chromophils and its' seven secretory cell types -
=Answer>>
Regulation of anterior pituitary is achieved by: -
=Answer>> feedback from hypothalamic releasing-
inhibitory hormones and factors, and feedback from
target gland hormones (cortisol, estrogen).
Growth Hormone secretion is controlled by 2 hormones
from the __________________, ______________________and
________________ - =Answer>> hypothalamus, Growth
Hormone-releasing hormone (GHRH) which releases,
and somatostatin which inhibits GH.
GH is released by the? - =Answer>> GH is released
from the pituitary in a pulsatile fashion, and overall
secretion peaks during adolescence.
GH is essential for what? - =Answer>> Growth, effects
of aging, sleep, nutritional status, stress, and
reproductive hormones
Anabolic functions of GH are mediated by? -
=Answer>> partially by insulin-like growth factors
(IGF's) or also called somatomedins.
IGF (insulin-like growth factors) - =Answer>> IGF-1,
and IGF-2, IGF-1 most biologically active. IGF-2 causes
a negative effect on tissue thus balancing IGF-1
Pineal Gland - =Answer>> Located in the brain and
composed of photoreceptive cells that secrete
melatonin.
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