What can antipsychotics do to help patients with schizophrenia? Right Ans
- - Alleviate symptoms
- CANNOT CURE
- Effectively treat acute exacerbations of schizophrenia
- Reduce number of relapses
- Lessen effects of relapses
What should the nurse be aware about antipsychotics
compliance/noncompliance? Right Ans - - Psychotic symptoms will return
for sure w/ medication noncompliance
- Even with medication compliance, psychosis can still occur
(Nothing is 100% bb)
First-generation antipsychotics are (classification based on MOA) Right
Ans - Dopamine (D2 receptor) antagonists
Interactions between FGAs and CNS depressants (alcohol, barbiturates,
antihistamines, sedatives, benzodiazepines) can do what? What should the
nurse teach? Right Ans - Can further potentiate CNS depression - No
drinking or CNS depressants
How long does it take antipsychotics to become effective? Right Ans - 2 to 6
weeks
True or False: Antipsychotics are addictive Right Ans - False
True or False: Antipsychotics are lethal in overdose Right Ans - False
How should antipsychotics be discontinued? Right Ans - Gradually
discontinued to minimize the discontinuation syndrome (dizziness, nausea,
tremors, insomnia, pain, anxiety)
What risks all antipsychotics have? Right Ans - Impaired swallowing
Drooling
Risk of choking
Risk for falls
Orthostatic hypotension
, Sedation
Gait impairment
What side effects all antipsychotics have? Right Ans - - Drowsiness
- Dizziness (orthostasis)
- Lowered seizure threshold
- Anticholinergic effects (dry mouth, flushed skin, blurred vision, constipation,
urinary retention, tachycardia, dilated pupils)
What are the pros of long-acting injectable (LAI) antipsychotics? Right Ans
- - Can be administered every 2-4 weeks or even months
- Reduce medication conflict
- IMPROVE MEDICATION ADHERENCE
- KEEP PT STABLE BETTER
What is the con of LAI antipsychotic? Right Ans - Patients may feel like they
have less control over their treatment
Which patient would likely be more beneficial to take LAI antipsychotics?
Right Ans - Patients with poor compliance due to paranoia, disorganized
thinking OR unable to OR prefer taking PO meds
What kind of schizophrenic symptoms can FGAs treat? Right Ans - ONLY
(+) symptoms
What adverse effects are more likely to occur in FGAs? Right Ans - -
Extrapyramidal symptoms (EPSs) (1)
- Tardive dyskinesia (TD) (2)
- Neuroleptic malignant syndrome (NMS)
- Body temperature alterations (hyperthermia associated w/ NMS is more
common)
- Orthostatic hypotension
- Liver impairment (injury, jaundice)
What side effects are more likely to occur with FGAs? Right Ans - -
Photosensitivity
- Cataracts
- Hyperprolactinemia
- Sexual dysfunction (impotence, anorgasmia)
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