TESTBANK h
RUBIN'S PATHOLOGY: h
CLINICOPATHOLOGIC
h
FOUNDATIONS OF MEDICINE
h h h
7th Edition By David S. Strayer, Emanuel Rubin
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TESTBANK h
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
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h
Table of Contents:
h h
Chapter 1: Cell Adaptation, Injury and Death
h h h h h h
Chapter 2: Inflammation
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Chapter 3: Repair, Regeneration and Fibrosis
h h h h h
Chapter 4: Immunopathology
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Chapter 5: Neoplasia
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Chapter 6: Developmental and Genetic Diseases
h h h h h
Chapter 7: Hemodynamic Disorders
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Chapter 8: Environmental and Nutritional Pathology
h h h h h
Chapter 9: Infectious and Parasitic Diseases
h h h h h
Section II: Pathogenesis of Systemic Conditions Expandable section
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Chapter 10: Aging
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Chapter 11: Systemic Autoimmune Diseases
h h h h
Chapter 12: Sepsis
h h
Chapter 13: Obesity and Diabetes Mellitus
h h h h h
Chapter 14: The Pathology of Pregnancy
h h h h h
Chapter 15: The Amyloidoses
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Section III: Diseases of Individual Organ SystemsExpandable section
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Chapter 16: Blood Vessels
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Chapter 17: The Heart
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Chapter 18: The Respiratory System
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Chapter 19: The Gastrointestinal Tract
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Chapter 20: The Liver and Biliary System
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Chapter 21: The Pancreas
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Chapter 22: The Kidney
h h h
Chapter 23: The Lower Urinary Tract and Male Reproductive System
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Chapter 24: The Female Reproductive System and Peritoneum
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Chapter 25: The Breast
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Chapter 26: Hematopathology
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Chapter 27: The Endocrine System
h h h h
Chapter 28: The Skin
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Chapter 29: The Head and Neck
h h h h h
Chapter 30: Bones, Joints and Soft Tissue
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Chapter 31: Skeletal Muscle and Peripheral Nervous System
h h h h h h h
Chapter 32: The Central Nervous System
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Chapter 33: The Eye
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Chapter 34: Forensic Pathology
h h h
,Rubin's Pathology: Clinicopathologic Foundations of Medicine
h h h h h
Chapter 1: Cell Adaptation, Injury and Death
h h h h h h h
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
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1. hof:
A) release of stored calcium from the mitochondria.
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B) improved intracellular volume regulation. h h h
C) decreased influx across the cell membrane. h h h h h
D) attraction of calcium to fatty infiltrates. h h h h h
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
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2. Adaptation to the reduced size of the liver leads to _
h h h of the remaining liver cells.
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A) metaplasia
B) organ atrophy h
C) compensatory hyperplasia h
D) physiologic hypertrophy h
A person eating peanuts starts choking and collapses. His airway obstruction is partially
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cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
h h h h h h h h h h h h h h
3. caused a cerebral infarction and resulting
h h h _ in the brain. h h h h h h
A) caspase activation h
B) coagulation necrosis h
C) rapid phagocytosis
h
D) protein p53 deficiency h h
Bacteria and viruses cause cell damage by
h h h h h h , which is unique from the intracellular
h h h h h h
4. damage caused by other injurious agents.
h h h h h h
A) disrupting the sodium/potassium ATPase pump h h h h
B) interrupting oxidative metabolism processes h h h
C) replicating and producing continued injury h h h h
D) decreasing protein synthesis and function h h h h
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
h h h h h h h h h h h h h h
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
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A) destroying phospholipids in the cell membrane. h h h h h
B) altering the immune response of the cell.
h h h h h h
C) disrupting calcium storage in the cell. h h h h h
D) inactivation of enzymes and mitochondria. h h h h
, 6. Injured cells have impaired flow of substances through the cell membrane as a result of:
h h h h h h h h h h h h h h
A) increased fat load. h h
B) altered permeability.h
C) altered glucose utilization.
h h
D) increased surface receptors. h h
7. Reversible adaptive intracellular responses are initiated by:
h h h h h h
A) stimulus overload. h
B) genetic mutations. h
C) chemical messengers. h
D) mitochondrial DNA. h
8. Injured cells become very swollen as a result of:
h h h h h h h h
A) increased cell protein synthesis. h h h
B) altered cell volume regulation.
h h h
C) passive entry of potassium into the cell.
h h h h h h
D) bleb formation in the plasma membrane.
h h h h h
A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He steps on
h h h h h h h h h h h h h h
a piece of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
h h h h h h h h h h h h h h h h h
9. cell death is characterized by:
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A) rapid apoptosis. h
B) cellular rupture. h
C) shrinkage and collapse. h h
D) chronic inflammation. h
A 99-year-old woman has experienced the decline of cell function associated with age. A
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10. group of theories of cellular aging focus on programmed:
h h h h h h h h h
A) changes with genetic influences. h h h
B) elimination of cell receptor sites. h h h h
C) insufficient telomerase enzyme. h h
D) DNA mutation or faulty repair.
h h h h
An 89-year-old female patient has experienced significant decreases in her mobility and
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stamina during a 3-week hospital stay for the treatment of a femoral head fracture. Which of
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the following phenomena most likely accounts for the patients decrease in muscle function
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11. that underlies her reduced mobility?
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A) Impaired muscle cell metabolism resulting from metaplasia
h h h h h h
B) Dysplasia as a consequence of inflammation during bone remodeling
h h h h h h h h
C) Disuse atrophy of muscle cells during a prolonged period of immobility
h h h h h h h h h h
RUBIN'S PATHOLOGY: h
CLINICOPATHOLOGIC
h
FOUNDATIONS OF MEDICINE
h h h
7th Edition By David S. Strayer, Emanuel Rubin
h h h h h h h
TESTBANK h
,Test Bank Rubin's Pathology: Clinicopathologic Foundations of Medicine 7th Edition
h h h h h h h h
h
Table of Contents:
h h
Chapter 1: Cell Adaptation, Injury and Death
h h h h h h
Chapter 2: Inflammation
h h
Chapter 3: Repair, Regeneration and Fibrosis
h h h h h
Chapter 4: Immunopathology
h h
Chapter 5: Neoplasia
h h
Chapter 6: Developmental and Genetic Diseases
h h h h h
Chapter 7: Hemodynamic Disorders
h h h
Chapter 8: Environmental and Nutritional Pathology
h h h h h
Chapter 9: Infectious and Parasitic Diseases
h h h h h
Section II: Pathogenesis of Systemic Conditions Expandable section
h h h h h h h
Chapter 10: Aging
h h
Chapter 11: Systemic Autoimmune Diseases
h h h h
Chapter 12: Sepsis
h h
Chapter 13: Obesity and Diabetes Mellitus
h h h h h
Chapter 14: The Pathology of Pregnancy
h h h h h
Chapter 15: The Amyloidoses
h h h
Section III: Diseases of Individual Organ SystemsExpandable section
h h h h h h h
Chapter 16: Blood Vessels
h h h
Chapter 17: The Heart
h h h
Chapter 18: The Respiratory System
h h h h
Chapter 19: The Gastrointestinal Tract
h h h h
Chapter 20: The Liver and Biliary System
h h h h h h
Chapter 21: The Pancreas
h h h
Chapter 22: The Kidney
h h h
Chapter 23: The Lower Urinary Tract and Male Reproductive System
h h h h h h h h h
Chapter 24: The Female Reproductive System and Peritoneum
h h h h h h h
Chapter 25: The Breast
h h h
Chapter 26: Hematopathology
h h
Chapter 27: The Endocrine System
h h h h
Chapter 28: The Skin
h h h
Chapter 29: The Head and Neck
h h h h h
Chapter 30: Bones, Joints and Soft Tissue
h h h h h h
Chapter 31: Skeletal Muscle and Peripheral Nervous System
h h h h h h h
Chapter 32: The Central Nervous System
h h h h h
Chapter 33: The Eye
h h h
Chapter 34: Forensic Pathology
h h h
,Rubin's Pathology: Clinicopathologic Foundations of Medicine
h h h h h
Chapter 1: Cell Adaptation, Injury and Death
h h h h h h h
Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result
h h h h h h h h h h h h h
1. hof:
A) release of stored calcium from the mitochondria.
h h h h h h
B) improved intracellular volume regulation. h h h
C) decreased influx across the cell membrane. h h h h h
D) attraction of calcium to fatty infiltrates. h h h h h
The patient is found to have liver disease, resulting in the removal of a lobe of his liver.
h h h h h h h h h h h h h h h h h
2. Adaptation to the reduced size of the liver leads to _
h h h of the remaining liver cells.
h h h h h h h h h h h h
A) metaplasia
B) organ atrophy h
C) compensatory hyperplasia h
D) physiologic hypertrophy h
A person eating peanuts starts choking and collapses. His airway obstruction is partially
h h h h h h h h h h h h
cleared, but he remains hypoxic until he reaches the hospital. The prolonged cell hypoxia
h h h h h h h h h h h h h h
3. caused a cerebral infarction and resulting
h h h _ in the brain. h h h h h h
A) caspase activation h
B) coagulation necrosis h
C) rapid phagocytosis
h
D) protein p53 deficiency h h
Bacteria and viruses cause cell damage by
h h h h h h , which is unique from the intracellular
h h h h h h
4. damage caused by other injurious agents.
h h h h h h
A) disrupting the sodium/potassium ATPase pump h h h h
B) interrupting oxidative metabolism processes h h h
C) replicating and producing continued injury h h h h
D) decreasing protein synthesis and function h h h h
The patient has a prolonged interruption in arterial blood flow to his left kidney, causing
h h h h h h h h h h h h h h
5. hypoxic cell injury and the release of free radicals. Free radicals damage cells by:
h h h h h h h h h h h h h h
A) destroying phospholipids in the cell membrane. h h h h h
B) altering the immune response of the cell.
h h h h h h
C) disrupting calcium storage in the cell. h h h h h
D) inactivation of enzymes and mitochondria. h h h h
, 6. Injured cells have impaired flow of substances through the cell membrane as a result of:
h h h h h h h h h h h h h h
A) increased fat load. h h
B) altered permeability.h
C) altered glucose utilization.
h h
D) increased surface receptors. h h
7. Reversible adaptive intracellular responses are initiated by:
h h h h h h
A) stimulus overload. h
B) genetic mutations. h
C) chemical messengers. h
D) mitochondrial DNA. h
8. Injured cells become very swollen as a result of:
h h h h h h h h
A) increased cell protein synthesis. h h h
B) altered cell volume regulation.
h h h
C) passive entry of potassium into the cell.
h h h h h h
D) bleb formation in the plasma membrane.
h h h h h
A diabetic patient has impaired sensation, circulation, and oxygenation of his feet. He steps on
h h h h h h h h h h h h h h
a piece of glass, the wound does not heal, and the area tissue becomes necrotic. The necrotic
h h h h h h h h h h h h h h h h h
9. cell death is characterized by:
h h h h h
A) rapid apoptosis. h
B) cellular rupture. h
C) shrinkage and collapse. h h
D) chronic inflammation. h
A 99-year-old woman has experienced the decline of cell function associated with age. A
h h h h h h h h h h h h h
10. group of theories of cellular aging focus on programmed:
h h h h h h h h h
A) changes with genetic influences. h h h
B) elimination of cell receptor sites. h h h h
C) insufficient telomerase enzyme. h h
D) DNA mutation or faulty repair.
h h h h
An 89-year-old female patient has experienced significant decreases in her mobility and
h h h h h h h h h h h
stamina during a 3-week hospital stay for the treatment of a femoral head fracture. Which of
h h h h h h h h h h h h h h h h
the following phenomena most likely accounts for the patients decrease in muscle function
h h h h h h h h h h h h h
11. that underlies her reduced mobility?
h h h h h
A) Impaired muscle cell metabolism resulting from metaplasia
h h h h h h
B) Dysplasia as a consequence of inflammation during bone remodeling
h h h h h h h h
C) Disuse atrophy of muscle cells during a prolonged period of immobility
h h h h h h h h h h
